【摘要】 目的：分析全胰切除术（TP）后营养干预及血糖管理对低血糖的防治效果。方法：选取上海市第一人民医院酒泉医院于2020年5月—2024年5月收治的30例TP患者进行研究，以随机颜色球抽取法分为对照组和观察组，各15例。对照组术后进行常规管理，观察组术后给予营养干预+血糖管理，比较两组干预效果。结果：观察组术后并发症总发生率显著低于对照组（P<0.05）。术后1周，与对照组比较，观察组空腹血糖水平、血糖波动平均幅度（MAGE）和低血糖发生次数均更低，差异有统计学意义（P<0.05）。术后1周，观察组前白蛋白、维生素D水平和中长链脂肪乳供能均高于对照组，差异有统计学意义（P<0.05）。结论：对TP后患者进行营养干预与血糖管理可有效改善营养指标，减少低血糖等并发症的发生，实现对血糖的有效管理，促进患者康复。更多还原

【Abstract】 Objective: To analyze the effect of nutritional intervention and glycemic management on the prevention and treatment of hypoglycemia after total pancreatectomy(TP). Methods: A total of 30 patients who underwent TP at Shanghai First People’s Hospital Jiuquan Hospital between May 2020 and May 2024 were selected and randomly divided into a control group and an observation group using a colored ball drawing method, with 15 patients in each group. The control group received conventional postoperative management, while the observation group received nutritional intervention combined with glycemic management. The two groups were compared. Results: The incidence of postoperative complications in the observation group was significantly lower than that in the control group(P < 0.05). At 1 week after surgery, the observation group showed significantly lower fasting blood glucose, mean amplitude of glycemic excursions(MAGE), and frequency of hypoglycemic events compared to the control group(P < 0.05). Additionally, the observation group had higher levels of prealbumin, vitamin D, and energy supply from medium-and long-chain fat emulsions than the control group(P < 0.05). Conclusion: Nutritional intervention and glycemic management in patients after TP can effectively improve nutritional indicators, reduce the occurrence of complications such as hypoglycemia, achieve effective glycemic control, and promote patient recovery.更多还原