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基于OCT测量GCC厚度在近视性视神经病变中的研究进展
Research progress on GCC thickness in MON based on optical coherence tomography
【摘要】 近视导致的众多眼底病变已深受关注,而对近视性视神经病变(MON)关注却少之甚少,一部分近视患者因视神经病变而失去视力,而这种视力损害很少会引起关注,以致疾病进展。视网膜神经节细胞(RGCs)的损伤可通过黄斑区神经节细胞复合体(GCC)等参数的变化来反映,一定程度上反映了视神经的损害,相干光层析成像术(OCT)的引入很大程度上促进了眼科领域的发展,其对视网膜细微结构的检测水平可与组织病理学相提并论。本文就OCT技术在近视眼中检测GCC的变化进行综述,旨在为MON的诊断、鉴别提供临床思路,以期提高对MON的密切关注。
【Abstract】 Many fundus lesions caused by myopia have been paid much attention, but little attention has been paid to myopia-associated optic neuropathy(MON), a part of myopia patients lose their vision due to optic neuropathy, and this visual impairment rarely causes concern, resulting in disease progression. The damage to retinal ganglion cells(RGCs) can be reflected by the changes of ganglion cell complex(GCC) and other parameters in the macular region, which, to some extent, reflects the damage to the optic nerve. The introduction of optical coherence tomography(OCT) has greatly promoted the development of the field of ophthalmology, and its level of detection of the fine structure of the retina is comparable to that of histopathology. This article reviews the changes of GCC detected by OCT in myopia, aiming to provide clinical ideas for the diagnosis and differentiation of MON, so as to improve the close attention of MON.
【Key words】 Optical coherence tomography; Myopia-associated optic neuropathy; Ganglion cell complex; Retinal nerve fiber layer;
- 【文献出处】 临床眼科杂志 ,Journal of Clinical Ophthalmology , 编辑部邮箱 ,2025年03期
- 【分类号】R778.11;R774.6
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