【摘要】 目的 了解青海省在碘缺乏病（IDD）干预期内出生的8～10岁儿童智力发展现状，分析孕妇碘营养改善与子代智力发育的关联性，为优化碘缺乏病防治策略提供科学依据。方法 2023年7月，采用横断面研究方法在青海省2市6州各选择1个县，每县各随机抽取1个城市和1个农村小学校，每所小学抽取在校8～10岁儿童（男女各半、年龄均衡）,采用联合型瑞文测验中国儿童常模第三次修订版（CRT）,针对城市儿童采用城市版常模（CRT-CC3）、针对农村儿童采用农村版常模（CRT-RC3）分别进行智商（IQ）评估。结果 共调查2 751名儿童，IQ中位数为107(P₂₅～P₇₅:100～115),“智力落后”（IQ≤69）的比率仅为0.58%（16/2 751）。不同地区之间，城市、乡村儿童IQ比较，差异有统计学意义（Z=-8.851,P<0.001）。不同年龄之间，8、9、10岁组儿童IQ比较，差异有统计学意义（H=178.978,P<0.001）;两两比较显示，8岁组与9岁组、8岁组与10岁组、9岁组与10岁组均有统计学意义（P<0.001）。不同性别之间，男、女儿童IQ比较，差异无统计学意义（Z=-1.633,P=0.103）。结论 青海省通过以孕妇家庭为核心的综合碘营养干预措施，显著促进了子代儿童的智力发育，全省儿童智力发育已整体达到“中上”水平，但未来仍需重点加强农村地区碘营养干预力度。更多还原

【Abstract】 Objective To understand the current status of intellectual development of 8-10-year-old children born during the intervention period of iodine deficiency disorders（IDD） in Qinghai Province, analyze the correlation between the improvement of iodine nutrition in pregnant women and the intellectual development of their offspring, and provide a scientific basis for optimizing the prevention and control strategies of IDD.Methods In July 2023,a cross-sectional study was conducted.One county was selected from each of the two cities and six prefectures in Qinghai Province.One urban and one rural primary school were randomly selected from each county.Children aged 8 to 10（half male and half female, with balanced age） were randomly selected from each primary school.The Third Revised Edition of the Chinese Children’s Norm（CRT） of the Combined Raven’s Test was adopted.Intelligence quotient（IQ） assessment was conducted respectively for urban children using the urban version norm（CRT-CC3） and for rural children using the rural version norm（CRT-RC3）.Results A total of 2 751 children were investigated.The median IQ was 107(P₂₅-P₇₅:100-115),and the rate of "intellectual disability"（IQ≤69） was only 0.58%（16/2 751）.There was a statistically significant difference in IQ between urban and rural children in different regions（Z=-8.851,P<0.001）.Among different ages, the comparison of IQ among children in the 8-,9-,and 10-year-old groups showed statistically significant differences（H=178.978,P<0.001）.Pairwise comparisons showed that there were statistically significant differences between the 8-year-old group and the 9-year-old group, the 8-year-old group and the 10-year-old group, and the 9-year-old group and the 10-year-old group（P<0.001）.There was no statistically significant difference in IQ between male and female children of different genders（Z=-1.633,P=0.103）.Conclusion Through comprehensive iodine nutrition intervention measures centered on pregnant women’s families in Qinghai Province, the intellectual development of offspring children has been significantly promoted.The intellectual development of children in the province has generally reached the "upper-middle" level, but in the future, the intensity of iodine nutrition intervention in rural areas still needs to be strengthened as a priority.更多还原