【摘要】 目的 探讨基于Rockall危险性积分的分层干预在直肠癌消化道出血患者中的应用效果。方法 将60例直肠癌消化道出血患者按干预方法的不同分为常规干预组28例和分层干预组32例，常规干预组患者实施常规干预，分层干预组患者实施基于Rockall危险性积分的分层干预。比较两组患者临床症状改善时间、住院时间、血液指标[血红蛋白（Hb）、前白蛋白（PAB）、总蛋白（TP）]、应激指标[丙二醛（MDA）、超氧化物歧化酶（SOD）]和住院期间并发症发生情况。结果 分层干预组患者止血时间、呕吐消失时间、肠鸣音恢复时间、住院时间均短于常规干预组，差异均有统计学意义（P﹤0.05）。入院第7天，两组患者Hb、PAB、TP、SOD水平均升高，MDA水平均下降，且分层干预组患者Hb、PAB、TP、SOD水平均高于常规干预组，MDA水平低于常规干预组，差异均有统计学意义（P﹤0.05）。分层干预组患者并发症总发生率低于常规干预组，差异有统计学意义（P﹤0.05）。结论 基于Rockall危险性积分的分层干预可促进直肠癌消化道出血患者临床症状缓解，改善机体血液指标和应激指标水平，降低并发症发生风险，具有临床推广应用价值。更多还原

【Abstract】 Objective To explore the application effect of stratified intervention based on Rockall risk score in rectal cancer(RC) patients complicated with gastrointestinal bleeding(GIB). Method A total of 60 RC patients with GIB were divided into the routine intervention group(28 cases) and the stratified intervention group(32 cases) according to different intervention methods. The routine intervention group received routine intervention, and the stratified intervention group received stratified intervention based on Rockall risk score. The improvement time of clinical symptoms, length of hospital stay, blood indexes [hemoglobin(Hb), prealbumin(PAB), total protein(TP)], stress indexes [malondialdehyde(MDA), superoxide dismutase(SOD)] and complications during hospitalization were compared between the two groups.Result The hemostasis time, vomiting disappearance time, bowel sound recovery time and hospitalization time of the stratified intervention group were shoter than those of the routine intervention group, and the differences were statistically significant(P<0.05). On the 7th day of admission, the levels of Hb, PAB, TP and SOD in the two groups were increased,and the levels of MDA were decreased, and the levels of Hb, PAB, TP and SOD in the stratified intervention group were higher than those in the routine intervention group, and the level of MDA was lower than that in the routine intervention group, and the differences were statistically significant(P<0.05). The total incidence of complications in the stratified intervention group was lower than that in the routine intervention group, and the difference was statistically significant(P<0.05). Conclusion Stratified intervention based on Rockall risk score can promote the clinical symptom relief in RC patients complicated with GIB, improve the levels of blood indexes and stress indexes, and reduce the risk of complications,which is worthy of clinical application.更多还原