【摘要】 目的：探讨2022—2023年河南郑州地区某骨专科三甲医院的医院感染现患率调查及变化趋势。方法：采用床旁调查和病历调查相结合的方法，调查时间为2023年8月29日和2022年9月20日内的所有住院患者的医院感染现患率、病原体送检及抗菌药物使用情况。结果：两年医院感染现患率、例次率比较，差异无统计学意义（P>0.05），而两年社区感染现患率、例次率比较，差异有统计学意义（P<0.05）。2022年、2023年医院感染现患率最高的科室分别为微创骨科、下肢骨科Ⅰ。2023年治疗性使用抗菌药物患者病原体送检率高于2022年（P<0.05）。两年医院感染病例病原体送检率比较，差异无统计学意义（P>0.05）。2022年和2023年调查当日抗菌药物使用率分别为35.25%和42.09%，差异有统计学意义（P<0.05）。在抗菌药物的使用构成中，抗菌药物使用目的比较，差异无统计学意义（P>0.05）；抗菌药物联合应用分布比较，差异无统计学意义（P>0.05）。结论：该院以手术部位感染位居首位，与综合医院不同。今后重点工作是加强医院感染监测、手术部位感染管理，合理使用抗菌药物，进一步提高临床医师送检意识，持续降低抗菌药物日使用率。更多还原

【Abstract】 Objective: To investigate the survey and trend of hospital infection prevalence rate in a tertiary orthopedic hospital in Zhengzhou, Henan Province from 2022 to 2023. Methods: A combination of bedside investigation and medical record investigation was used to investigate the hospital infection prevalence rate, pathogen testing, and antibiotic use of all hospitalized patients between August 29, 2023 and September 20, 2022. Results: There was no significant difference in the prevalence rate and case rate of nosocomial infection between the two years(P>0.05), while there was significant difference in the prevalence rate and case rate of community infection between the two years(P<0.05). In 2022 and 2023, the departments with the highest prevalence of nosocomial infection were minimally invasive orthopedics and lower limb orthopedics I, respectively. The detection rate of pathogens in patients with therapeutic use of antibiotics in 2023 was higher than that in 2022(P<0.05). There was no significant difference in the pathogen submission rate of nosocomial infection cases between the two years(P>0.05). The utilization rate of antibiotics on the day of investigation in 2022 and 2023 was 35.25 % and 42.09 %, respectively, and the difference was statistically significant(P<0.05).In the composition of the use of antibiotics, there was no significant difference in the purpose of the use of antibiotics(P>0.05).There was no significant difference in the distribution of combined application of antibiotics(P>0.05). Conclusion: Surgical site infection ranked first in this hospital, which was different from that in general hospitals. In the future, the key work is to strengthen the monitoring of hospital infection, the management of surgical site infection, the rational use of antibiotics, further improve the awareness of clinicians, and continuously reduce the daily use rate of antibiotics.更多还原