【摘要】 目的 整合心脏手术患者围手术期谵妄预防的证据。方法 按照循证资源6S模型，自上而下逐级检索国内外相关数据库及网站，检索时间限定为2014年1月1日—2023年4月23日，由2名研究者独立进行文献质量评价和资料提取，整理出心脏手术患者围手术期谵妄预防的最佳证据。结果 最终共纳入12篇文献，其中3篇指南、5篇专家共识、3篇临床决策、1篇系统评价，从团队合作、危险因素识别、评估、诊断、非药物干预、药物干预6个方面汇总整理出38条最佳证据。结论 总结出有关心脏手术患者围手术期谵妄预防的最佳证据，可为临床医护人员制定相关管理方案和开展临床实践提供参考，建议在证据应用的基础上结合患者具体情况制定出个体化的谵妄预防方案。更多还原

【Abstract】 Objective To integrate the evidence on prevention of delirium in perioperative patients undergoing cardi-ac surgery. Methods In accordance with the 6S model of evidence-based resources, the top-down search of domestic and international relevant databases and websites was conducted one by one, and the search time was limited to January 1, 2014 to April 23, 2023. Two researchers independently conducted the literature quality assessment and information extrac-tion to compile the best evidence for perioperative delirium prevention in cardiac surgery patients. Results A total of 12 publications were eventually included, including 3 guidelines, 5 expert consensus, 3 clinical decision-making, and 1 sys-tematic evaluation. The 38 best pieces of evidence were summarized from 6 aspects: teamwork, risk factor identification, assessment, diagnosis, non-drug intervention and drug intervention. Conclusions To summarize the best evidence for perioperative prevention of delirium in patients undergoing cardiac surgery, which can provide a reference for clinical healthcare professionals to develop relevant management protocols and carry out clinical practice. It is recommend that in-dividualized delirium prevention protocols be developed based on the application of the evidence and in conjunction with patient-specific conditions.更多还原