【摘要】 目的:探讨生物膜联合喉模技术在声带粘连的预防和治疗中的临床效果。方法:回顾性分析复旦大学附属华山医院诊治的21例接受生物膜-硅胶喉模复合体技术防治声带粘连患者的基本资料、围手术期一般情况及治疗预后。结果:纳入21例患者中男19例(90.5%),女2例(9.5%),其中18例早期声门型喉癌(T1b)、1例双侧声带白斑及2例喉术后声带粘连患者。围术期均未发生喉模意外脱离，术后平均(22.4±2.6) d拆除硅胶模。术后定期复查，整体有效率为90.5%(19/21)。术后5例患者出现并发症(1例喉内感染、4例肉芽组织增生),经保守治疗后均痊愈。结论:本研究初步探索了生物膜材料在防治声带粘连中的可行性，该生物膜-硅胶喉模复合体技术操作简便，预防声带粘连效果良好，值得临床推广。更多还原

【Abstract】 Objective: To retrospectively analyze the clinical effect of biomaterial combined with silicone keel technology in the prevention and treatment of vocal folds adhesion. Methods: The basic data, perioperative conditions and prognosis of 21 cases of vocal folds adhesion treated by biofilm-silicone keel complex were retrospectively analyzed in Huashan Hospital Fudan University. Results: A total of 21 patients were enrolled in this study(19 males(90.5%), 2 females(9.5%). Among these patients, 18 cases of early glottic laryngeal carcinoma(T1b), 1 case of bilateral vocal folds leukoplecta and 2 cases of postoperative vocal folds adhesion. No accidental rupture of the silicone keel occurred during perioperative period, and the silicone keel was removed in 22.4±2.6 days. All patients were reviewed after removing the silicone keel, the overall effective rate was 90.5%(19/21). Postoperative complications occurred in 5 patients(1 laryngeal infection, 4 granulation tissue hyperplasia), all of whom were cured after conservative treatment. Conclusion: This study explored the feasibility of biomaterial in the treatment of vocal folds adhesion. The biomaterial-silicone keel complex technology is simple to operate and has effect on the prevention of vocal folds adhesions, which is worth of clinical promotion.更多还原