【摘要】 贝类毒素是由海洋中有毒藻类产生的有毒高分子化合物，贝类通过摄食有毒藻类在体内蓄积，严重威胁消费者健康。本文综述了贝类毒素的分类及亲水作用色谱(HILIC)的保留机理和特点。重点介绍了亲水作用色谱-质谱联用(HILIC-MS)技术在贝类毒素测定方面的应用研究进展，并提出了HILIC-MS在贝类毒素检测分析方面的发展趋势。更多还原

【Abstract】 Shellfish toxins are toxic macromolecular compounds produced by toxic algae in the ocean. Shellfish accumulate in their body by ingesting toxic algae, which seriously threatens the health of consumers. In this paper, we reviewed the classification of shellfish toxins and the retention mechanism and characteristics of hydrophilic interaction chromatography(HILIC). The application of hydrophilic interaction chromatography-mass spectrometry(HILIC-MS) in determining shellfish toxins was introduced, and the development trend of HILIC-MS in the detection and analysis of shellfish toxins was put forward.更多还原