【摘要】 在电化学条件下进行亚硝基苯与缺电子炔烃的偶联反应，实现了碳碳三键的断裂并生成α-羰基芳酰胺。反应在阴极单电子还原产生亚硝基自由基，随后对炔烃进行自由基加成并通过分子内重排断键一步合成α-羰基芳酰胺。通过对反应机理进行研究，表明α-羰基芳酰胺的氧来自于氧气。反应过程中使用氧气球提供氧气，10 mA恒定电流进行电解。该方法条件温和，操作简单，无需添加金属催化剂和额外的添加剂，具有良好的底物适用范围。更多还原

【Abstract】 The coupling reaction of nitrosobenzene with electron-deficient alkynes under electrochemical conditions was reported. The carbon-carbon triple bond was broken and α-carbonyl aromatic amide was generated. The reaction produced nitroso radicals by cathodic single electron reduction, followed by free radical addition of alkynes and one-step synthesis of α-carbonyl aromatic amide by intramolecular rearrangement of bonds. Through the study of the reaction mechanism, it was shown that the oxygen of α-carbonyl aromatic amide came from oxygen. During the reaction, oxygen spheres were used to provide oxygen, and electrolysis was performed at a constant current of 10 mA to obtain α-carbonyl aromatic amide. For the method, it has mild conditions, simple operation, no need to add metal catalysts and additional additives, and has a good substrate scope.更多还原