【摘要】 生物化学与分子生物学是一门在分子水平解释生命现象、探讨疾病发生机制的课程。在教学过程中，仍存在学生学习能力参差不齐、课程与临床及科研的融合度不高、缺乏有针对性的智慧教学模式等问题。本研究秉承以学生为中心的教学理念，以人文、结果、问题、实验为导向，充分依托智慧教室开展线下智慧教学，并应用网络教学平台开展线上隐性分层教学，在评价方面实行了师生反馈、督导反馈及同行反馈的三位一体动态反馈机制。基于上述措施，本课程建立并推广了线上线下相结合的O2O智慧教学模式，进一步完善了本课程的课堂授课内容，同时也提升了授课团队的信息化授课能力，帮助医学生对本课程有了更深入的理解。更多还原

【Abstract】 Biochemistry and Molecular Biology is a course that explains life phenomena at the molecular level and explores the mechanism of disease.In the teaching process，there are still some problems such as uneven students’ learning abilities，low integration of courses with clinical and scientific research，and lack of targeted smart teaching models.This study takes a student-centered teaching concept.It is oriented by humanities，results，problems and experiments，fully relies on smart classrooms to carry out offline smart teaching，and applies the online teaching platform to carry out implicit stratified teaching mode.In terms of evaluation，a three-in-one dynamic feedback mechanism of teacher-student feedback，supervisory feedback and peer feedback has been implemented.Based on the above measures，this course has established and promoted the O2O smart teaching mode combining online and offline，which further improves the classroom teaching content of this course，and also improves the information teaching ability of the teaching team，and helping medical students to have a deeper understanding of this course.更多还原