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β内酰胺类-β内酰胺酶抑制剂复方制剂儿科临床应用专家共识
Expert consensus on pediatric clinical application of β-lactam-β-lactamase inhibitor compounds
【摘要】 内酰胺类-β内酰胺酶抑制剂复方制剂是治疗儿童感染性疾病的常用药物。虽然已有针对成人的β内酰胺类复方制剂应用的共识,但由于儿童不同于成人的生理特点,亟需一个专门针对儿童的β内酰胺类复方制剂应用的指导文件。该共识从β内酰胺类复方制剂的药物学特点、儿童药代动力学特点、儿童药效学特点、在常见儿童感染性疾病中的作用及药物管理等方面,对该类药物在儿童中的应用给出了全面建议,以规范儿科临床的合理使用。
【Abstract】 The compounds of β-lactamases and β-lactamases inhibitors is a commonly used drug to treat infectious diseases in children. Although there is a consensus on β-lactam compounds preparations for adults,because of children’s differences from adults in physiological characteristics,there is an urgent need for a guiding document concerning β-lactam compounds for children. This consensus gives comprehensive suggestions on the application of β-lactam compounds in children from the aspects of pharmacological characteristics,pharmacokinetic characteristics,pharmacodynamic characteristics of children,role in common infectious diseases of children and drug management,so as to standardize the appropriate use in pediatric clinics.
【Key words】 β-lactam-β-lactamase inhibitor compounds; child; consensus;
- 【文献出处】 中国实用儿科杂志 ,Chinese Journal of Practical Pediatrics , 编辑部邮箱 ,2023年09期
- 【分类号】R985
- 【下载频次】80