【作者】
王金涛；
马莎；
王含；
巴茂文；
陈先文；
胡兴越；
刘艺鸣；
承欧梅；
王玉凯；
周凡；
许顺良；
沈岳飞；
陈伟；
窦荣花；
刘学东；
韩彦青；
王华龙；
丁岩；
潘小玲；
黄卫；
陈蕾；
卢宏；
徐刚；
王刚；
【Author】
WANG Jin-tao;MA Sha;WANG Han;BA Mao-wen;CHEN Xian-wen;HU Xing-yue;LIU Yi-ming;CHENG Ou-mei;WANG Yu-kai;ZHOU Fan;XU Shun-liang;SHEN Yue-fei;CHEN Wei;DOU Rong-hua;LIU Xue-dong;HAN Yan-qing;WANG Hua-long;DING Yan;PAN Xiao-ling;HUANG Wei;CHEN Lei;LU Hong;XU Gang;WANG Gang;Department of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine;Department of Neurology, The First People’s Hospital of Yunnan Province;Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences;Department of Neurology, Yantai Yuhuangding Hospital Affiliated to Qingdao University;Department of Neurology, The First Affiliated Hospital of Anhui Medical University;Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine;Department of Neurology, Qilu Hospital of Shandong University;Department of Neurology, The First Affiliated Hospital of Chongqing Medical University;Department of Neurology, The First People’s Hospital of Foshan;Department of Neurology, Jingzhou Central Hospital;Department of Neurology, The Second Hospital of Shandong University;Department of Neurology, The First Affiliated Hospital of Guangxi Medical University;Department of Neurology, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine;Department of Neurology, Cangzhou Hospital of Integrated Traditional and Western Medicine;Department of Neurology, Xijing Hospital, Air Force Military Medical University of Chinese PLA;Department of Neurology, Shanxi Cardiovascular Hospital Affiliated to Shanxi Medical University;Department of Neurology, The First Hospital of Hebei Medical University;Department of Neurology, Xuanwu Hospital, Capital Medical University;Department of Neurology, Jinhua Municipal Central Hospital;Department of Neurology, The Second Affiliated Hospital of Nanchang University;Department of Neurology, Tianjin Huanhu Hospital;Department of Neurology, The First Affiliated Hospital of Zhengzhou University;School of Public Health, Shanghai Jiaotong University;
【通讯作者】
王刚;
【机构】
上海交通大学医学院附属瑞金医院神经内科；
云南省第一人民医院神经内科；
中国医学科学院北京协和医院神经科；
青岛大学附属烟台毓璜顶医院神经内科；
安徽医科大学第一附属医院神经内科；
浙江大学医学院附属邵逸夫医院神经内科；
山东大学齐鲁医院神经内科；
重庆医科大学附属第一医院神经内科；
广东省佛山市第一人民医院神经内科；
湖北省荆州市中心医院神经内科；
山东大学第二医院神经内科；
广西医科大学第一附属医院神经内科；
上海交通大学医学院附属第九人民医院神经内科；
河北省沧州中西医结合医院神经内科；
空军军医大学西京医院神经内科；
山西医科大学附属心血管病医院神经内科；
河北医科大学第一医院神经内科；
首都医科大学宣武医院神经内科；
浙江省金华市中心医院神经内科；
南昌大学第二附属医院神经内科；
天津市环湖医院神经内科；
郑州大学第一附属医院神经内科；
上海交通大学公共卫生学院；
【摘要】 目的 基于国内运动障碍专病门诊初步总结功能性运动障碍的流行病学和临床特征。方法与结果 纳入2023年8-9月国内22个临床医学中心运动障碍专病门诊新诊断的593例运动障碍患者，其中功能性运动障碍37例（6.24%），器质性运动障碍556例（93.76%）。流行病学特征比较，功能性运动障碍患者新型冠状病毒感染（χ~2=4.217,P=0.040）和合并精神心理症状（χ~2=18.694,P=0.000）比例高于器质性运动障碍患者，年龄（t=3.757,P=0.000）、发病年龄（t=3.720,P=0.000）和高血压比例（χ~2=4.736,P=0.030）低于器质性运动障碍患者；临床特征比较，功能性运动障碍患者震颤（χ~2=3.955,P=0.047）和肌阵挛（Fisher确切概率法：P=0.011）比例高于器质性运动障碍患者，帕金森综合征（χ~2=8.491,P=0.004）和步态障碍（χ~2=5.028,P=0.025）比例低于器质性运动障碍患者。结论 我国功能性运动障碍患者年龄、发病年龄，以及新型冠状病毒感染、高血压、精神心理症状、震颤、肌阵挛、帕金森综合征和步态障碍比例与器质性运动障碍患者存在差异。更多还原
【Abstract】 ObjectiveTo preliminarily summarize the epidemiological and clinical characteristicsof functional movement disorder(FMD) based on movement disorders clinic in China.Methods and ResultsA total of 593 patients with movement disorders newly diagnosed in movement disorders clinic of22 clinical medical centers from August to September in 2023 were included, including 37 patients(6.24%)with FMD and 556 patients(93.76%) with organic movement disorder. Comparison of the epidemiologicalcharacteristics of the 2 groups, the proportions of corona virus disease(COVID-19) infection(χ~2= 4.217, P =0.040) and psychopsychological symptoms(χ~2= 18.694, P = 0.000) in the FMD group were higher than thosein the organic movement disorder group, while age(t = 3.757, P = 0.000), age of onset(t = 3.720, P = 0.000)and proportion of hypertension(χ~2= 4.736, P = 0.030) were lower than those in the organic movementdisorder group. Comparison of the clinical characteristics of the 2 groups, the FMD group had higherproportions of tremor(χ~2= 3.955, P = 0.047) and myoclonus(Fisher′s exact probability: P = 0.011) than theorganic movement disorder group, and the proportions of parkinsonism(χ~2= 8.491, P = 0.004) and gaitdisorder(χ~2= 5.028, P = 0.025) were lower than those in the organic movement disorder group.ConclusionsThe age and age of onset, as well as the proportions of COVID-19 infection, hypertension,psychopsychological symptoms, tremor, myoclonus, parkinsonism and gait disorder with FMD were differentfrom those with organic movement disorder in China.更多还原
【基金】 上海市“医苑新星”杰出青年医师计划项目（项目编号：2019-72）~~
