【摘要】 心房颤动（简称房颤）是最常见的持续性心律失常，可显著增加患者卒中的风险，并且与非房颤相关的卒中相比，房颤相关的卒中更致残和致命。由于口服抗凝药物可有效降低房颤患者的血栓栓塞风险，因此制定合理的抗凝策略是预防卒中、实现房颤综合管理的关键。文章围绕房颤抗凝治疗的这一临床问题，对房颤抗凝的适宜人群、抗凝药物的选择以及特殊人群的抗凝治疗等方面进行了总结，为房颤患者规范化抗凝提供一定临床参考。更多还原

【Abstract】 As the most common sustained arrhythmia,atrial fibrillation(AF)significantly increases the risk of stroke.Compared with stroke without AF,AF-related stroke is more fatal and disabling. Since oral anticoagulation is effective in reducing thromboembolic risk,developing a rational anticoagulation strategy is the key to preventing stroke and achieving comprehensive management of AF. This article focuses on anticoagulation in AF and summarizes the appropriate population for anticoagulation,the selection of anticoagulants,and anticoagulation in special populations to provide some clinical references for the anticoagulation in AF.更多还原