【摘要】 目的：探讨Nd:YAG 1 064 nm激光与超脉冲点阵CO2激光治疗面部萎缩性痤疮瘢痕美学效果。方法：选择2018年1月-2021年1月笔者医院收治的94例患者，按照随机数字表法分为对照组（47例）与研究组（47例）。对照组接受Nd:YAG 1 064 nm激光治疗；研究组接受超脉冲点阵CO₂激光治疗。比较两组临床疗效、愈合时间、误工时间、温哥华瘢痕量表（Vancouver scar scale,VSS）评分及不良反应。结果：研究组治疗总有效率95.74%，较对照组80.85%高（P<0.05）；研究组结痂时间、完全脱痂时间均比对照组短（P<0.05）；研究组治疗后柔软度、色泽、血管分布、厚度评分均低于对照组（P<0.05）；研究组治疗后社会功能、自我感知、痤疮症状评分高于对照组（P<0.05）；两组不良反应总发生率相比无差异（P>0.05）。结论：相比Nd:YAG 1 064 nm激光，超脉冲点阵CO₂激光治疗面部萎缩性痤疮瘢痕可以明显缩短患者愈合时间，更好改善瘢痕，美学效果更佳。更多还原

【Abstract】 Objective The aim of this study was to investigate the cosmetic results of 1 064 nm Nd:YAG laser and ultra-pulse fractional CO₂ laser in the treatment offacial atrophic acne scars. Methods This study included 94 patients with facial atrophic acne scars who were admitted to the hospital from January 2018 to January 2021. The patients were divided into the control group and the study group by random number table method, with 47 cases in each group. Patients in the control group were treated with 1 064 nm Nd:YAG laser, and those in the study group were treated with ultra-pulse fractional CO₂ laser. The two groups were compared on clinical effects, healing time, loss of working time, vancouver scar scale（VSS） scores and adverse reactions. Results The total treatment response rate in the study group（95.74%） was higher than that in the control group（80.85%）（P<0.05）. The scab formation time and complete scab removal time of the study group were shorter than those of the control group（P<0.05）. After treatment, the scores of softness, color, blood vessel distribution, and thickness in the study group were lower than those of the control group（P<0.05）. The scores of social function, self-perception, and acne symptoms were higher than those of the control group（P<0.05）. There was no significant difference between the two groups in the total incidence of adverse reactions（P>0.05）. Conclusion Compared with 1 064 nm Nd:YAG laser, treatment with ultra-pulse fractional CO₂ laser for facial atrophic acne scars can significantly shorten the healing time, and improve scars, with better cosmetic results.更多还原