节点文献
CRISPR/Cas系统在新型冠状病毒肺炎快速诊断中的应用
Application of CRISPR/Cas Systems in the Rapid Diagnosis of Coronavirus Disease 2019
【摘要】 近年来,基于规律成簇间隔的短回文重复序列(clustered regularly interspaced short palindromic repeats,CRISPR)及其相关蛋白(CRISPR-associated protein, Cas)系统的新型分子诊断工具,为病原体的诊断开辟了新的机遇。该文将关注现有和正在研究的CRISPR/Cas系统用于新型冠状病毒肺炎(coronavirus disease 2019, COVID-19)快速诊断的潜在能力,并重点探讨其在临床中的应用和面临的挑战。
【Abstract】 In recent years, emerging molecular diagnostic tools based on clustered regularly interspaced short palindromic repeats/CRISPR-associated(CRISPR/Cas) systems have opened up new opportunities for pathogen diagnosis. This article will focus on the potential capabilities of the existing and under-research CRISPR/Cas systems for rapid diagnosis of the coronavirus disease 2019(COVID-19), and discuss their clinical applications and challenges.
【关键词】 间隔的短回文重复序列及其相关蛋白系统;
新型冠状病毒;
新型冠状病毒肺炎;
快速诊断;
【Key words】 CRISPR/Cas systems; SARS-CoV-2; COVID-19; rapid diagnosis;
【Key words】 CRISPR/Cas systems; SARS-CoV-2; COVID-19; rapid diagnosis;
【基金】 广西临床重点专科建设项目(202015)
- 【文献出处】 现代检验医学杂志 ,Journal of Modern Laboratory Medicine , 编辑部邮箱 ,2022年03期
- 【分类号】R563.1;R440
- 【被引频次】1
- 【下载频次】185