【摘要】 目的 探究多索茶碱与氨茶碱对支气管哮喘患者的临床治疗效果。方法 在2017年1月—2019年12月福建省疾病预防控制中心第二门诊收治的支气管哮喘患者中方便选取209例作为研究对象并随机分为两组。研究组（n=105）采用多索茶碱进行治疗，对照组（n=104）采用氨茶碱进行治疗，比较两组临床治疗效果。结果 研究组治疗总有效率为98.10%，高于对照组的89.42%，差异有统计学意义（χ~2=6.736,P<0.05）；经治疗，两组患者肺部功能指标均有所改善，且研究组FVC、FEV1以及PEF指标均高于对照组，研究组患者症状消失用时均短于对照组，差异有统计学意义（P<0.05）；研究组不良反应率为1.90%低于对照组的11.54%，差异有统计学意义（χ~2=7.759,P<0.05）；经治疗，两组患者生活质量评分均有所提升，且研究组高于对照组，差异有统计学意义（P<0.05）；研究组治疗满意度为97.14%高于对照组的87.50%，差异有统计学意义（χ~2=6.872,P<0.05）。结论 将多索茶碱合理应用到支气管哮喘患者临床治疗过程中，具有十分显著的应用效果，其能够有效改善患者临床症状，同时有助于改善患者呼吸系统功能，促进患者康复。更多还原

【Abstract】 Objective To explore the clinical therapeutic effect of doxofylline and aminophylline in patients with bronchial asthma. Methods A total of 209 bronchial asthma patients admitted to the second clinic of Fujian Center for Disease Control and Prevention from January 2017 to December 2019 were selected conveniently as the research subjects and randomly divided into two groups. Among them, the study group(n=105) was treated with doxofylline, and the control group(n=104) was treated with aminophylline, and the clinical effects of the two groups were compared. Results The total effective rate of the study group was 98.10%, which was higher than that of the control group(89.42%), and the difference was statistically significant(χ~2=6.736, P<0.05). After treatment, the pulmonary function indexes were improved in two groups, and the indexes of FVC, FEV1 and PEF in the study group were higher than those in the control group, and the disappearance time of symptoms in the study group was shorter than those in the control group, and the differences were statistically significant(P<0.05). The ADR rate of the study group was 1.90% lower than that of the control group(11.54%), and the difference was statistically significant(χ~2=7.759, P<0.05). After treatment, the quality of life scores were improved in two groups, and the study group was higher than the control group, and the difference was statistically significant(P<0.05). The treatment satisfaction of the study group was 97.14% higher than that of the control group 87.50%, and the difference was statistically significant(χ~2=6.872, P<0.05). Conclusion The rational application of doxofylline in the clinical treatment of patients with bronchial asthma has a very significant application effect. It can effectively improve the clinical symptoms of patients, and at the same time help to improve the function of the respiratory system and promote the recovery of patients.更多还原