【摘要】 目的探究超声造影(CEUS)联合声辐射力脉冲成像技术(ARFI)对甲状腺结节良恶性评估的临床应用价值。方法选取2017年6月至2019年8月我院甲乳外科经手术病理证实的75例甲状腺结节病变患者进行研究。采用问卷调查获取患者相关资料,患者均进行CEUS、ARFI检查,鉴别诊断甲状腺良、恶性结节性病变,观察其图像特征,并分析CEUS与ARFI诊断价值。结果 CEUS诊断甲状腺良恶性结节准确率为87.50%,CEUS诊断结果与病理诊断Kappa值为0.715(P<0.001);ARFI诊断甲状腺良恶性结节总准确率为88.75%,ARFI诊断结果与病理诊断Kappa值为0.736(P<0.001);两种方式联合诊断甲状腺良恶性结节总准确率为91.25%,两种方式联合诊断与病理诊断Kappa值为0.810(P<0.001);两者联合诊断甲状腺良恶性结节与病理诊断的一致性优于单纯的CEUS与ARFI。结论 CEUS联合ARFI对甲状腺结节良恶性诊断准确率较高,优于单独应用CEUS和ARFI检查。更多还原

【Abstract】 Objective To investigate the clinical application value of contrast enhanced ultrasound(CEUS)combined with acoustic radiation force imaging(ARFI) in the assessment of benign and malignant thyroid nodules. Methods Between June 2017 and August 2019, 75 patients with thyroid nodular lesions confirmed by surgery and pathology in our breast surgery were enrolled. Questionnaires were used to obtain patient-related information. All patients underwent CEUS and ARFI examinations to identify benign and malignant nodular lesions of the thyroid gland, observe their image characteristics, and analyze the diagnostic value of CEUS and ARFI. Results The accuracy rate of CEUS diagnosis in benign and malignant thyroid nodules was 87.50%, the Kappa value of CEUS diagnosis and pathological diagnosis was 0.715, P<0.001.The total accuracy of ARFI diagnosis in benign and malignant thyroid nodules was 88.75%, the Kappa value of ARFI diagnosis result and pathological diagnosis was 0.736, P<0.001. The total accuracy of the two methods in the diagnosis of benign and malignant thyroid nodules was 91.5%, and the Kappa value of the two methods in the combined diagnosis and pathological diagnosis was 0.810, P<0.001; The agreement of combined diagnosis in benign and malignant thyroid nodules with pathological diagnosis was better than that of CEUS and ARFI alone. Conclusion CEUS and ARFI have a higher accuracy rate in the diagnosis of benign and malignant thyroid nodules, which is better than CEUS and ARFI alone.更多还原