【摘要】 目的分析结直肠锯齿状息肉,包括锯齿状腺瘤[传统锯齿状腺瘤(TSA)、无蒂锯齿状腺瘤(SSA/P)]与增生性息肉(HP)的内镜特征。方法选取行结肠镜检查的7225例患者为研究对象, 2260例患者有息肉,其中结直肠锯齿状息肉197例,包括锯齿状腺瘤患者43例[TSA患者29例(作为TSA组),SSA/P患者14例(作为SSA/P组)], HP患者154例(作为HP组)。比较三组患者的一般资料、内镜下特征,分析锯齿状腺瘤/HP发生的影响因素。结果锯齿状腺瘤检出率为0.60%(43/7225),其中TSA检出率为0.40%(29/7225), SSA/P检出率为0.19%(14/7225);HP检出率为2.13%(154/7225)。三组患者的息肉发病部位、病变有无蒂、病变直径、病变大体分型比较,差异有统计学意义(P<0.05)。Logistic回归分析显示,息肉的部位、直径为锯齿状腺瘤/HP发生的独立危险因素(P<0.05)。结论通过对锯齿状息肉,包括TSA、SSA/P与HP的内镜特征进行分析,结合病理检查,可更好的分辨三者的差异,指导临床治疗及随访。更多还原

【Abstract】 Objective To analyze the endoscopic characteristics of colorectal serrated polyps, including serrated polyps [traditional serrated adenoma(TSA), sessile serrated adenoma/polyps(SSA/P)] and hyperplastic polyp(HP). Methods There were 7225 patients who underwent colonoscopy selected as the research subjects. 2260 patients had polyps, of which 197 patients with colorectal serrated polyps, including 43 patients with serrated adenoma [29 patients with TSA(as TSA group), 14 patients with SSA/P(as SSA/P group)], 154 patients with HP(as HP group). The general data and endoscopic features of the three groups were compared, and the influencing factors of serrated adenoma/HP were analyzed. Results The detection rate of serrated adenoma was 0.60%(43/7225), of which the detection rate of TSA was 0.40%(29/7225), the detection rate of SSA/P was 0.19%(14/7225); the detection rate of HP 2.13%(154/7225). There was statistically significant difference in the location of polyps, whether the lesion had a pedicle, diameter of the lesion, and general type of the lesion in the three groups(P<0.05). Logistic regression analysis showed that the location and diameter of polyps were independent risk factors for serrated adenoma/HP(P<0.05). Conclusion By analyzing the endoscopic features of serrated polyps, including TSA, SSA/P and HP, combining with the pathological examination, can effectively distinguish the differences among the three groups and guide the clinical treatment and follow-up visit.更多还原