【摘要】 妊娠滋养细胞肿瘤(gestational trophoblastic neoplasia,GTN)与妊娠密切相关,多继发于葡萄胎妊娠,也可继发于流产、足月妊娠、异位妊娠及早产。GTN常发生转移,并且转移早且广泛,主要播散至肺部。对于特殊部位(本文泛指生殖系统、肺部之外)的转移性GTN,部分患者以转移部位症状、体征首次就诊,子宫及肺部影像学检查及病理活检均未发现病灶,可能与原发病灶消失,特殊部位转移灶进展有关。这类患者的诊治方案、预后及预后相关影响因素,值得进一步探究。更多还原

【Abstract】 Gestational trophoblastic neoplasia(GTN) is a group of tumors closely associated with pregnancy. The malignant forms can arise after any type of pregnancy, mainly after hydatidiform mole, the rest can occur after a spontaneous abortion, a term, ectopic pregnancy or a premature birth. The metastasis of GTN appears early with many sites involved, which are commonly found in the lungs. Some patients with GTN in special sites(only those outside the reproductive system and lungs are discussed in this article) see their doctors only because of their symptoms related to special metastatic lesions, while there is no evidence of GTN in genitalia or lungs after imaging or histopathological examination. It may be related to the disappearance of primary lesions and development of metastatic lesions in special sites. This review aims to summarize the diagnosis, treatment protocols and prognosis of GTN in special sites.更多还原