【摘要】 目的:通过静脉注射人免疫球蛋白药物(IVIG)治疗婴幼儿毛细支气管炎,观察其临床疗效并总结护理干预对治疗效果的影响。方法:统计2017年1月至2019年1月中本院接收并经相关检查确诊为毛细支气管炎婴幼儿共284例,需排除39例合并心肺功能不全、喘憋严重患儿,将245例患儿作为本次研究对象,均在常规治疗基础上给予IVIG治疗,按照护理模式不同将其划分为观察组与对照组,为观察组患儿提供全面、综合性护理干预,而对照组患儿仅接受临床常规护理方法,观察两组患儿经治疗及护理前后细胞因子与IgG指标值变化;观察患儿症状及体征恢复正常时间;观察患儿家属对护理服务满意度情况;并对出院患儿进行随访,检测其肺部功能。结果:经治疗护理后,两组患儿较治疗前细胞炎性因子均有明显好转,其中观察组患儿IL-6、IgG以及NF-kB等指标好转程度较优于对照组(P<0.05);观察组患儿体温下降、呼吸恢复正常、喘憋缓解时间与肺部湿啰音消失、胸片吸收时间均短于对照组,另外在短期疗效中,观察组患儿入睡时间、吸氧时间以及住院时间同样短于对照组(P<0.05);观察组患儿家长总满意度为95.12%,明显高于对照组的85.26%(P<0.05);观察组患儿无1例出现不良反应,对照组仅出现2例注射局部皮肤红肿疼痛现象,差异对比无统计学意义(P> 0.05);对出院患儿提供为期1年随访发现,观察组中肺功能恢复正常患儿比例明显高于对照组(P<0.05)。结论:使用人免疫球蛋白治疗毛细支气管炎婴幼儿疗效确切,同时需配合人性化、综合性护理干预措施,以增进药物作用,促进患儿早日康复,提高该病治愈率。更多还原

【Abstract】 Objective:To observe the clinical efficacy of intravenous injection of Human Immunoglobulin(IVIG) in the treatment of bronchiolitis in infants, and to sum up the nursing experience. Methods: Statistics 284 cases of infants with bronchiolitis diagnosed and received by the hospital from January 2017 to January 2019,39 cases were excluded for heart and lung function with incomplete,asthmatic children with serious,245 cases were selected as the research object,were given IVIG treatment on the basis of routine treatment,according to the nursing mode different divided into observation group and control group,provided comprehensive and comprehensive nursing intervention for the patients in the observation group,while the control group received only routine clinical care,the two groups were observed before and after the treatment and nursing of cytokines and IgG value changes observed the symptoms and signs of recovery time;observed the families of children with nursing service satisfaction;and followed up and detected the lung function of children with discharge. Results: After treatment and nursing,the two groups of children were significantly better than those before treatment,and the improvement of IL-6,IgG and NF-kB in the observation group was better than that in the control group(P < 0.05);The observation group with hypothermia,breath,dyspnea remission time and pulmonary rales disappeared,chest X-ray absorption time was shorter than the control group,in the short term treatment,observation group with sleep time, oxygen time and hospitalization time was also shorter than the control group(P < 0.05);The total satisfaction of the parents in the observation group(95.12%) was significantly higher than that in the control group(85.26%)(P < 0.05);No adverse reactions occurred in 1 case in the observation group,the control group only appeared in the injection of local skin redness and pain of the phenomenon,the difference was not significant(P > 0.05);The results showed that the children in the observation group were significantly higher than those in the control group after 1 year of follow-up(P < 0.05). Conclusion: The curative effect of the treatment of bronchiolitis in infants using Human Immunoglobulin exactly,at the same time with the comprehensive nursing intervention measures to improve humanity,and drug action,promote the rehabilitation of infants,improve the cure rate.更多还原