【摘要】 目的了解上海市收治的境外输入性儿童新型冠状病毒(SARS-CoV-2)感染病例的流行病学和临床特征。方法收集2020年3月14日至2020年4月8日在上海市入境的38例经呼吸道标本核酸检测阳性确诊的SARS-CoV-2感染的儿童病例资料,分析其流行病学史、临床表现、实验室检查、胸部影像学以及治疗和转归情况。结果 38例患儿中,无症状感染16例(42.1%),非重症肺炎14例(36.8%),轻型8例(21.1%); 37例(97.4%)来自欧洲和北美; 26例(68.4%)无明确感染病例接触史或者聚集发病,12例(31.6%)有家庭内或学生宿舍内感染病例接触史。非肺炎组和肺炎组病例性别和年龄差异无统计学意义(P>0.05)。14例肺炎病例随访影像学均显示肺部病灶吸收治愈。16例无症状感染者在住院期间未出现症状和肺部影像学异常。7例有发热,热程平均2.5 d,11例有咳嗽,5例有咽痛,4例有鼻塞和流涕症状,6例使用过1～6 d羟氯喹治疗。38例均治愈出院,住院时间平均(18.5±3.4) d。结论境外输入性儿童SARS-CoV-2感染病例以无症状感染常见。有肺炎和无肺炎实验室检查结果无明显特异性。无症状感染者和非重症病例不推荐常规胸部影像学复查。更多还原

【Abstract】 Objective To understand the epidemiological and clinical features of the 38 imported pediatric cases of SARSCo V-2 infection in Shanghai. Methods The clinical data were collected from the 38 imported pediatric cases with laboratoryconfirmed SARS-CoV-2 infection from March 14 to April 8 2020. The epidemiological history,clinical presentations,laboratory findings,chest radiological findings,treatment and outcomes were analyzed. Results Of the 38 imported cases,16( 42.1%) were asymptomatic,14( 36.8%) had non-severe pneumonia,and 8( 21. 1%) had mild illness. There were 37 cases( 97. 4%) from Europe and North America,26 cases( 68. 4%) without a definitive contact history,and 12 cases( 31. 6%) linked with family cluster infection or exposure to suspected cases in school dormitory. There was no statistical difference between the pneumonia group and the non-pneumonia group in terms of gender and age( P>0.05). The 14 pneumonia cases showed absorption of lung lesions by follow-up chest radiology,and the 16 asymptomatic cases did not develop any symptoms and radiological abnormalities during hospitalization. Seven cases had fever with a mean duration of 2.5 days,11 had mild cough,5 had sore throat,and 4 had runny nose. Hydroxychloroquine was used in the 6 cases for 1-6 days. All cases recovered uneventfully with a mean length of hospitalization of 18.5±3.4 days. Conclusion Asymptomatic infection was common among the imported pediatric cases of COVID-19 from abroad. There was no obvious difference of the laboratory findings between the pneumonia group and the non-pneumonia group. Routine re-detection of radiography is not recommended for asymptomatic and mild cases.更多还原