【摘要】 吻合口瘘是食管癌、贲门癌患者术后最常见的严重并发症,其临床发生率和病死率均较高,且发生原因较复杂,是食管癌、贲门癌患者手术治疗成功的关键因素。本研究通过分析通畅引流、抗感染及营养支持等保守方式治疗,结果发现符合条件的吻合口瘘患者愈合效果佳;而对于不易进行保守治疗的患者,应积极行手术治疗,主要方式为单纯瘘口修补术、吻合口重建术和食管旷置;此外,食管内覆膜支架置入术、胃镜下吻合口瘘黏膜夹闭术及生物蛋白胶封堵新技术的应用,同样可提高术后吻合口瘘的治愈率。更多还原

【Abstract】 Anastomotic fistula is the most common serious postoperative complication in patients with esophageal and gastric cardia carcinoma. It is of high clinical incidence and mortality and complex causes, so it is the key factor in the successful surgical treatment of esophageal and gastric cardia carcinoma. In this study, via the analysis of conservative treatment such as unobstructed drainage, anti infection and nutritional support, it was found that the patients with qualified anastomotic fistula had good healing efficacy, while those who were not easy to be treated conservatively should be actively provided with surgical treatment. The main surgical methods were as follows: simple fistula repair, anastomotic reconstruction and esophageal exclusion. In addition, the application of esophageal stent placement, endoscopic mucosal clamping of fistula and bioprotein fibrin glue could also improve the healing rate of anastomotic fistula.更多还原