【摘要】 目的探讨在急性非ST段抬高型心肌梗死(NSTEMI)合并心力衰竭患者中应用地尔硫卓治疗对心功能及不良心血管事件(MACE)的影响。方法选择我院2018年8月至2019年8月接收的NSTEMI合并心力衰竭患者86例,随机分为2组,各43例。所有患者均给予基础治疗,在此基础上,对照组加用硝酸甘油治疗,观察组加用地尔硫卓治疗,治疗1周后,比较两组左室舒张末期容积(LVEDV)、左室射血分数(LVEF)及MACE。结果治疗1周后,两组LVEDV较治疗前降低,LVEF较治疗前升高,且观察组优于对照组,差异有统计学意义(p<0.05);观察组MACE发生率为6.98%,低于对照组的20.93%,差异有统计学意义(p<0.05)。结论在NSTEMI合并心力衰竭患者中应用地尔硫卓治疗效果显著,可有效改善心功能,减少MACE发生。更多还原

【Abstract】 Objective To investigate the effect of diltiazem on cardiac function and adverse cardiovascular events(MACE) in patients with acute non ST elevation myocardial infarction(ansemi) and heart failure. Methods From August 2018 to August 2019, 86 patients with heart failure in ansemi were selected and divided into two groups according to the blind pumping method, 43 cases in each group. All patients were given basic treatment. On this basis,the control group was treated with nitroglycerin, and the observation group was treated with diltiazem. After one week of treatment, left ventricular end diastolic volume(LVEDV), left ventricular ejection fraction(LVEF) and mace were compared between the two groups. Results After one week of treatment, LVEDV decreased and LVEF increased in the two groups, and the difference was statistically significant(p<0.05); the incidence of mace in the observation group was 6.98%, lower than 20.93% in the control group, and the difference was statistically significant(p<0.05).Conclusions diltiazem can improve cardiac function and reduce the incidence of mace.更多还原