【摘要】 目的探讨极低出生体质量儿(VLBW)和超低出生体质量儿(ELBW)的临床转归及其危险因素。方法回顾性分析2017年1月至2019年9月在安徽省儿童医院就诊的138例ELBW、VLBW的临床资料,分析影响患儿临床转归的危险因素。结果患儿临床转归与胎龄、体质量、双胎或多胎、母亲围产期病史以及母亲既往病史有关(P<0.05)。患儿体质量、双胎或多胎为负性临床结局的保护因素(P<0.05),母亲围产期病史中胎膜早破是负性临床结局的危险因素(P<0.05)。结论 ELBW与VLBW的生存率较低、并发症多,临床预后影响因素多。在提高临床诊疗和护理质量的同时,应加强围生期保健治疗及护理宣教,及早发现影响ELBW与VLBW临床结局的不利因素,及时干预,改善预后。更多还原

【Abstract】 Objective To explore the clinical outcome and risk factors of very low birth weight infants(VLBW) and extremely low birth weight(ELBW) infants. Methods A retrospective analysis was performed on the clinical data of 138 cases of ELBW and VLBW infants admitted to the NICU of Anhui Provincial Children’s Hospital from January 2017 to October 2019. Multi-factor regression analysis was used to assess the risk factors of children’s clinical prognosis. Results The clinical outcomes of children had statistically significant differences with their gestational age, body weight, twin or multiple, maternal perinatal medical history and past history(P<0.05).The patients’ body weight, twin or multiple were protective factors for negative clinical outcomes(P<0.05), and premature rupture of membranes in mothers’ perinatal history was a risk factor for negative clinical outcomes(P<0.05).Conclusions ELBW and VLBW have low survival rates, many complications, and many factors affecting clinical prognosis. For the improvement of the quality of clinical diagnosis and treatment, we should also strengthen perinatal health care treatment and nursing education, identify the adverse factors that affect the clinical outcomes of ELBW and VLBW as soon as possible, and intervene in time so asto improve the prognosis.更多还原