【摘要】 目的研究颈髓损伤伴体位性低血压(OH)患者尿中儿茶酚胺代谢产物香草扁桃酸(vanillylmandelic acid,VMA)含量变化,以探讨该类患者自主神经功能变化情况。方法收集颈髓损伤伴OH患者15例,颈髓损伤无OH患者17例,采用色谱法分别测定24 h尿VMA含量,并对测定结果进行统计学分析。结果颈髓损伤伴OH患者24 h尿VMA含量明显低于颈髓损伤无OH组[(12.4±3.27)μmol/24 h vs.(34.5±9.41)μmol/24 h,P<0.05]。结论颈髓损伤伴OH患者24 h尿VMA在评估脊髓损伤后自主神经张力变化有一定的临床意义。更多还原

【Abstract】 Objective To assess autonomic nerve function in patients with orthostatic hypotension(OH) after cervical spinal cord injury(SCI) by evaluating the level of urinary vanillylmandelic acid(VMA).Methods The level of 24 hours urinary VMA was determinated in 15 patients with OH after cervical SCI and 17 patients without OH by high-performance liquid chromatography.The results were statistically analyzed according to t-test analysis.Results The urinary VMA concentrations in persons with OH after cervical lesions were markedly reduced compared to patients without OH after cervical SCI [(12.4±3.27) μmol/24 h vs.(34.5±9.41) μmol/24 h,P <0.05].Conclusion The level of 24 h urinary VMA could have the potential to assess the autonomic nerve function in patients post SCI.更多还原