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肝型脂肪酸结合蛋白在糖尿病中的研究

Study on Hepatic Fatty Acid Binding Protein in Diabetes

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【作者】 王静郭宏敏

【Author】 WANG Jing;GUO Hong-min;Department of Endocrinology,Taicang Hospital of Traditional Chinese Medicine;Department of Geriatrics,Jiangsu Provincial Hospital of Traditional Chinese Medicine;

【机构】 太仓中医医院内分泌科江苏省中医院老年科

【摘要】 肝型脂肪酸结合蛋白(L-FABP)在肝脏、肾脏等组织细胞中表达。有研究表明,L-FABP与糖尿病的发生、发展密切相关。同时作为肾损伤的敏感指标,尿L-FABP成为糖尿病肾病早期诊断的标志物之一并能预测病情的转归。本文就肝型脂肪酸结合蛋白在糖尿病中的研究进展进行综述。

【Abstract】 Hepatic fatty acid binding protein(L-FABP) is expressed in tissue cells such as liver and kidney. Studies have shown that L-FABP is closely related to the occurrence and development of diabetes. At the same time, as a sensitive indicator of kidney injury, urinary L-FABP becomes one of the early markers of diabetic nephropathy and can predict the outcome of the disease. This article reviews the research progress of hepatic fatty acid binding protein in diabetes.

【基金】 太仓市级科技项目(编号:TC2018JCYL16)
  • 【文献出处】 医学信息 ,Medical Information , 编辑部邮箱 ,2019年18期
  • 【分类号】R587.1
  • 【被引频次】1
  • 【下载频次】126
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