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第六届肺动脉高压大会专家意见解读之二——肺动脉高压血流动力学定义和临床分类更新
Interpretation:recommendations of the 6st World Symposium on Pulmonary Hypertension(Ⅱ)——haemodynamic definitions and updated clinical classification of pulmonary hypertension
【摘要】 肺动脉高压(pulmonary hypertension)既往被定义为仰卧位静息状态下右心导管测得平均肺动脉压(m PAP)≥25mmHg。第六届肺动脉高压大会(WSPH)建议用mPAP>20 mmHg定义肺动脉压的异常升高,而要定义毛细血管前肺动脉高压需要加上PVR≥3 WU。关于肺动脉高压的临床分类,此次大会在第一大类动脉性肺动脉高压中新增了"1.5对钙离子通道阻滞剂(CCBs)长期有反应的肺动脉高压"并且用"1.6伴有明显肺静脉或肺毛细血管受累的PH"代替原有的"1’肺静脉闭塞病(PVOD)或肺毛细血管瘤样增生症(PCH)"。
【Abstract】 Pulmonary hypertension(PH)has been defined as mean pulmonary arterial pressure(mPAP)≥25 mmHg at rest,measured by right heart catheterisation. The 6 th WSPH suggested a new pressure level to define an abnormal elevation as the mPAP>20 mmHg and the need for PVR≥3 WU to define the presence of pre-capillary PH. Regarding clinical classification,the main changes were the inclusion in group 1 of a subgroup"pulmonary arterial hypertension(PAH)long-term responders to calcium channel blockers"and a subgroup"PAH with overt features of venous/capillaries involvement".
【Key words】 pulmonary hypertension; pulmonary arterial hypertension; mean pulmonary arterial pressure; pulmonary vascular resistance; PAH long-term responders to CCBs; PAH with overt features of venous; capillaries involvement;
- 【文献出处】 中国实用内科杂志 ,Chinese Journal of Practical Internal Medicine , 编辑部邮箱 ,2019年11期
- 【分类号】R544.1
- 【被引频次】4
- 【下载频次】386