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探讨腹腔镜术后联合注射用醋酸曲普瑞林对子宫内膜异位症治疗的临床疗效

Investigation on the Clinical Efficacy of Triptolide in the Treatment of Endometriosis with Laparoscopic Combined with Injection

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【作者】 赵银玲钱华袁冬兰吴翊群朱丹丹姜丽周姝

【Author】 ZHAO Yin-ling;QIAN Hua;YUAN Dong-lan;WU Yi-qun;ZHU Dan-dan;JIANG Li;ZHOU Shu;Department of Obstetrics and Gynecology, Taizhou People’s Hospital;

【通讯作者】 钱华;

【机构】 泰州市人民医院妇产科

【摘要】 目的分析腹腔镜术后联合注射用醋酸曲普瑞林对子宫内膜异位症治疗的临床疗效。方法研究将2013年1月—2015年1月期间该院妇科收治的80例子宫内膜异位症患者作为该次研究对象,对所有患者的病例资料进行回顾性分析,依据治疗方式的差异进行分组,使用腹腔镜手术+孕三烯酮进行治疗的患者为对照组,术后联合使用射用醋酸曲普瑞林治疗的为实验组,每组患者40例,对比两组患者的治疗效果、排卵时间、月经恢复时间和不良反应。结果实验组患者的治疗有效率为95.0%(38例),对照组患者的治疗有效率为80.0%(32例),两组患者治疗有效率差异有统计学意义(χ2=4.114,P<0.05);实验组患者不良反应发生率为7.5%(3例),对照组患者不良反应发生率为25.0%(10例),两组患者不良反应率数据对比差异有统计学意义(χ2=4.551,P<0.05);实验组患者停药后排卵时间为(22.73±5.25)d,月经恢复时间为(38.77±5.22)d,其数据较对照组更低,数据差异有统计学意义(t=3.928、6.107,P<0.05);实验组患者复发率为2.5%(1例),对照组患者复发率为15.0%(6例),两组数据差异有统计学意义(χ2=3.914,P<0.05)。结论腹腔镜术后联合注射用醋酸曲普瑞林治疗子宫内膜异位症可提升手术治疗,停药后卵巢恢复排卵和月经恢复快,同时减少术后并发症及复发率,临床应用价值较高,建议在积极进行推广。

【Abstract】 Objective To analyze the clinical efficacy of triptorelin combined with intraperitoneal injection for the treatment of en-dometriosis. Methods Eighty patients with endometriosis admitted to our hospital during the period from January 2013 to January 2015 were enrolled in this study. The medical records of all patients were retrospectively analyzed according to the differences in treatment methods. Patients treated with laparoscopic surgery + gestrinone were used as the control group. The experimental group was treated with triptorel acetate for injection. Each group had 40 patients, and the treatment of the two groups was compared, as well as the ef-fects, ovulation time, menstrual recovery time and adverse reactions. Results The effective rate of the experimental group was 95.0%(38 cases), and the effective rate of the control group was 80.0%(32 cases). There was a statistically significant difference in the ef-fective rate between the two groups(χ2=4.114, P<0.05). The incidence of adverse reactions in the experimental group was 7.5%(3 cases), and the incidence of adverse reactions in the control group was 25.0%(10 cases). There was a statistically significant difference in the adverse reaction rate between the two groups(χ2=4.551, P<0.05); the ovulation time of the experimental group was(22.73±5.25)d, and the recovery time of menstruation was(38.77±5.22)d. The data were lower than the control group, and the data were statistically significant(t=3.928, 6.107, P<0.05); the recurrence rate was 2.5%(1 case) in the experimental group and 15.0%(6 cases) in the control group. The difference between the two groups was statistically significant(χ2=3.914, P<0.05). Conclusion Laparoscopic combined with triptorelin for the treatment of endometriosis can improve the surgical treatment. After stopping the drug, the ovary can recover from ovulation and recovery of menstruation, and reduce the postoperative complications and recurrence rate, with high clinical application value, it is recommended to actively promote.

  • 【文献出处】 世界复合医学 ,World Journal of Complex Medicine , 编辑部邮箱 ,2019年09期
  • 【分类号】R711.71
  • 【被引频次】3
  • 【下载频次】30
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