【摘要】 【目的】观察通淋排石合剂口服配合邱氏穴按压治疗湿热型肾绞痛的临床疗效。【方法】将120例湿热型肾绞痛患者随机分为观察组和对照组,每组各60例。观察组给予通淋排石合剂口服配合邱氏穴按压治疗,对照组给予氟比洛芬酯联合山莨菪碱静滴治疗,观察2组患者治疗前和治疗15 min、30 min及60 min后疼痛视觉模拟量表(VAS)评分的变化情况,评价2组疼痛缓解疗效,并观察2组患者7 d内病情复发率和排石率情况。【结果】(1)治疗后,2组患者的疼痛VAS评分均较治疗前有不同程度下降(P<0.05或P<0.01),且观察组在治疗15 min后患者的疼痛VAS评分降低更明显,差异有统计学意义(P<0.05)。(2)在治疗15 min、30 min和60 min后,观察组患者疼痛缓解疗效的总有效率分别为75.00%、88.33%和90.00%,对照组患者分别为56.67%、83.33%和93.33%;观察组在治疗15 min后的疼痛缓解总有效率和总体疗效均优于对照组,差异均有统计学意义(P<0.05或P<0.01)。(3)随访7 d,2组患者均有部分病例失访,但差异无统计学意义(P>0.05);排除失访数据,观察组7 d内肾绞痛复发率为13.33%,低于对照组的25.00%,差异有统计学意义(P<0.05);观察组的排石率为53.33%,明显优于对照组的33.33%,差异有统计学意义(P<0.05)。【结论】通淋排石合剂口服配合邱氏穴按压治疗湿热型肾绞痛起效快、疗效确切,不仅简、便、效、廉,还能促进机体自身排石,是临床治疗湿热型肾绞痛的一种比较好的方法。更多还原

【Abstract】 Objective To observe the clinical effect of oral administration of Tonglin Paishi Mixture combined with Chiu’s point acupressure in the treatment of damp-heat type of renal colic. Methods A total of 120 renal colic patients with the damp-heat syndrome were randomly divided into observation group and control group,60 cases in each group. The observation group was given Tonglin Paishi Mixture combined with Chiu’s point acupressure,and the control group was treated with intravenous drip of flurbiprofen and anisodamine. The pain scores evaluated with Visual Analogue Scale(VAS)before treatment and after treatment for 15,30 and 60 minutes were observed,efficacy on pain relief was evaluated,and the relapse of renal colic and stone discharge rate within 7 days were detected in the two groups. Results(1)After treatment,VAS pain scores in the two groups were decreased to various degrees(P<0.05 or P<0.01 compared with those before treatment),and the decrease of VAS pain scores in the observation group after treatment for 15 min was superior to that in the control group at the same time point(P<0.05).(2)After treatment for 15,30 and 60 minutes,the total pain-relief effective rate in the observation group was 75.00%, 88.33%, 90.00%, respectively, and that in the control group was 56.67%, 83.33%,93.33%,respectively;the observation group had higher total pain-relief effective rate and overall efficacy than the control group after treatment for 15 min,the difference being statistically significant(P<0.05 or P<0.01).(3)During the 7-day follow-up,both of the observation group and the control group had some cases of being lost to follow-up,but the difference was not statistically significant(P>0.05). After excluding the patients being lost to follow-up,the relapse of renal colic within 7 days in the observation group was 13.33%,and was lower than that in the control group(25.00%),the difference being statistically significant(P < 0.05); the stone discharge rate in the observation group was 53.33%,and was lower than that in the control group(33.33%),the difference being statistically significant(P < 0.05). Conclusion Oral administration of Tonglin Paishi Mixture combined with Chiu’s point acupressure exerts rapid and certain efficacy in the treatment of damp-heat type of renal colic. The therapy has the advantages of being simple,practical,effective and economic,and can promote the automatic discharge of the stone.更多还原