【摘要】 目的观察加味百合地黄汤联合耳针治疗2型糖尿病(T2DM)伴睡眠障碍的临床疗效。方法将56例入选患者随机分为加味百合地黄汤联合耳针治疗观察组和佐匹克隆片联合耳针治疗对照组,进行为期28 d的治疗和观察,比较治疗前后匹兹堡睡眠质量指数量表(PSQI)、中医症状积分、汉密尔顿焦虑量表(HAMA)和糖化血清蛋白(GSP)的差异。结果2组患者的睡眠质量均得到改善(P<0.05);GSP和HAMA评分亦较治疗前下降(P<0.05)。观察组在改善PSQI因子睡眠质量、睡眠效率、日间功能障碍,烦燥易怒、口干咽燥、潮热盗汗中医症状积分及GSP水平方面优于对照组(P<0.05)。结论中药联合耳针治疗T2DM伴睡眠障碍疗效肯定,值得推广。更多还原

【Abstract】 Objective To observe the clinical effect of modified Baihe Dihuang Decoction combined with auriculotherapy for the treatment of type 2 diabetes accompanied by insomnia. Methods 56 patients were randomly divided into two groups: modified Baihe Dihuang Decoction combined with auriculotherapy group(treatment group) and Zopiclone Tablets group(control group). Both groups were treated for 28 days. Pittsburgh sleep quality index(PSQI), TCM symptom scores, Hamilton Anxiety Scale(HAMA) and Glycosylated serum protein(GSP) were observed before and after the treatment. Results Both two groups of patients were been improved in sleep quality(P<0.05), and GSP and HAMA scores were lowered than that before the treatment(P<0.05). Compared with the control group, the improvement of sleep quality, sleep efficiency, daytime dysfunction index, HAMA and TCM symptom scores in the treatment group were significantly improved(P<0.05). Conclusion Chinese herbal medicine combined with auriculotherapy is more effective on type 2 diabetes with insomnia, and is worth popularizing.更多还原