【摘要】 目的探讨18F-FDG PET/CT利尿延迟显像膀胱放射性廓清效果的影响因素。方法回顾性收集85例盆腔利尿延迟显像患者的PET/CT资料,测量膀胱常规及利尿延迟显像最大标准化摄取值（SUVmax）,记录延迟时间;分析常规显像膀胱SUVmax、呋塞米注射途径（静脉注射或肌内注射）、延迟时间、年龄、性别因素对利尿延迟显像膀胱SUVmax的影响。结果根据呋塞米注射途径不同,分为静脉注射组（n=34）和肌内注射组（n=51）,2组利尿延迟显像膀胱SUVmax分别为3.10（2.60,3.45）和2.90（2.30,3.90）,差异无统计学意义（Z=-0.894,P=0.372）;延迟显像时间分别为¹⁸F-FDG注射后（215.00±30.03）min和（198.43±25.19）min,差异有统计学意义（t=-2.655,P=0.010）。2组间年龄差异无统计学意义（t=1.150,P=0.253）,2组中不同性别患者间延迟显像膀胱SUV_max差异均无统计学意义（P均>0.05）。静脉注射组和肌内注射组利尿延迟显像膀胱SUV_max与延迟时间和患者年龄均无明显相关性。结论注射¹⁸F-FDG后充分水化、应用呋塞米利尿,约180min行盆腔延迟显像能显著降低膀胱放射性,患者年龄、性别、呋塞米注射途径对于膀胱放射性廓清效果无明显影响。更多还原

【Abstract】 Objective To investigate the impact factors of bladder radioactive washout on ¹⁸F-FDG PET/CT diuretic delayed imaging.Methods PET/CT data with pelvic delayed imaging of 85 patients were retrospectively analyzed.Maximal standardized uptake value（SUVmax）of the bladder on routine and delayed imaging and delayed time were measured.The influence of the bladder SUVmax on routine imaging,furosemide injection approaches（transvenous or intramuscular）,delayed time,patient’s age and gender on bladder SUVmaxon delayed imaging were respectively analyzed.Results The patients were divided into transvenous group（n=34）and intramuscular group（n=51）.The SUVmaxof bladder on delayed imaging was 3.10（2.60,3.45）of transvenous group and 2.90（2.30,3.90）of intramuscular group（Z=-0.894,P=0.372）.The delayed time was（215.00±30.03）min in transvenous group and（198.43±25.19）min in intramuscular group after ¹⁸F-FDG injection（t=-2.655,P=0.010）.No difference of patients’ age was found between the 2 groups（t=1.150,P=0.253）.SUV_maxof bladder on delayed imaging had no difference between different genders in both group（both P>0.05）.SUV_maxof bladder on delayed imaging had no correlation to delay time nor age in both group（all P>0.05）.Conclusion The radioactivity of the bladder decreases dramatically on delayed imaging performed about 180 min after ¹⁸F-FDG injection with prior enough hydration and furosemide diuresis.Patient’s age,gender and furosemide injection approaches has no obvious impact on bladder radioactive washout.更多还原