【摘要】 目的探讨综合干预措施对降低心外科住院患者医院感染的效果,为心外科住院患者医院感染的防控提供理论依据。方法选取2016年1月-12月医院心外科住院患者842例,根据综合干预措施实施时间分为两组,其中1-6月为干预前组,7-12月为干预后组,干预前组394例患者进行常规干预,干预后组448例患者给予综合干预措施,观察患者医院感染率、感染部位及病原菌分布情况。结果干预前组发生医院感染56例,感染率为14.21%,干预后组发生医院感染36例,感染率为8.04%,干预前组医院感染率高于干预后组(P<0.05);两组患者医院感染部位均以呼吸系统为主,干预前组占42.86%,干预后组占47.22%,两组比较差异无统计学意义;干预前组患者送检标本中分离出病原菌49株,干预后组分离出病原菌28株,共77株,其中革兰阴性菌51株,占66.23%,革兰阳性菌26株,占33.77%;干预前组检出多药耐药菌占53.06%,干预后组占28.57%(P<0.05)。结论综合干预措施的实施有助于降低心外科医院感染率,能较好预防多药耐药菌感染发生。更多还原

【Abstract】 OBJECTIVE To explore the effect of comprehensive interventions on reduction of incidence of nosocomial infections in hospitalized patients of cardiac surgery department so as to provide theoretical basis for prevention and control of nosocomial infections in the hospitalized patients of cardiac surgery department.METHODS A total of 842 patients who were hospitalized in cardiac surgery department from Jan 2016 to Dec 2016 were enrolled in the study and divided into the pre-intervention group(from January to June)and the post-intervention group(from July to December)according to the time of implementation of the comprehensive measures.The pre-intervention group with 394 cases was treated with conventional interventions,while the post-intervention group with448 cases was given comprehensive interventions.The incidence of nosocomial infections,infection sites and distribution of pathogens were observed.RESULTS Totally 56 patients had nosocomial infections in the pre-intervention group,with the infection rate 14.21%;totally 36 patients had nosocomial infections in the post-intervention group,with the infection rate 8.04%;the incidence of nosocomial infections of the pre-intervention group was significantly higher than that of the post-intervention group(P<0.05).The patients with respiratory system infection accounted for 42.86%in the pre-intervention group,47.22%in the post-intervention group,and there was no significant difference between the two groups.A total of 49 strains of pathogens were isolated from submitted specimens of the patients in the pre-intervention group,and 28 strains of pathogens were isolated in the pre-intervention group.Of the 77 strains of pathogens isolated,51(66.23%)were gram-negative bacteria,and 26(33.77%)were gram-positive bacteria;the multidrug-resistant organisms(MDROs)accounted for 53.06%in the pre-intervention group,28.57%in the post-intervention group(P<0.05).CONCLUSION The comprehensive interventions may contribute to the reduction of incidence of nosocomial infections in the cardiac surgery department and to the prevention of MDROs infection.更多还原