【摘要】 目的探讨胰腺与其他消化器官神经内分泌肿瘤(NEN) CT特点的差异。方法收集2013年10月～2016年12月之间经病理证实的消化系统NEN患者56例(胰腺26例,其他30例)共57个病灶,其中男31例,女25例,平均年龄为54. 7岁。对患者的临床及影像学资料进行回顾性分析。CT表现包括:病灶的发生部位、最大径、形态、平扫密度、边缘情况、强化程度、强化均匀度、强化曲线类型,同时记录临近结构及血管有无受累、有无腹水、以及腹膜、淋巴结及其他脏器的转移等。分析胰腺与其他消化器官NEN之间上述影像学表现之间的差异。结果在胰腺和其他器官NEN之间,患者年龄、病理G分级、平均最大径均存在统计学差异(P <0. 05)。在各CT表现中,动脉及静脉期强化程度、静脉及延迟期强化均匀度、肿瘤边界、形态、腹膜转移等均具有明显统计学差异(P <0. 05),但肿瘤钙化、平扫密度、动脉期强化均匀度、延迟期强化程度、强化曲线类型、临近结构的浸润、血管侵犯、淋巴结转移、远处脏器转移、腹水等均未见统计学差异(P> 0. 05)。结论胰腺和其他消化器官的NEN的生物学行为和CT表现存在一定的差异,动静脉期强化程度、静脉及延迟期强化均匀度等一些指标对于两者的鉴别具有一定的意义。更多还原

【Abstract】 Objective To investigate the differences in the CT features of neuroendocrine neoplasms( NEN) between pancreasand other digestive organs. Methods A total of 56 patients with pathologically confirmed 57 NENs of the digestive system werecollected from October 2013 to December 2016( 31 males and 25 females) with an average age of 54. 7 years. The clinical andimaging data of the patients were retrospectively analyzed. CT manifestations were evaluated including the location of the lesion,maximum diameter,shape,density on plain scan,the edge,the enhancing degrees,enhancing uniformity,the enhancing curvetypes,involvement of the adjacent structures and blood vessels,ascites,metastasis of peritoneal and lymph nodes,and other or-gans. The differences in CT findings of NENs between pancreas and other digestive organs were analyzed. Results There werestatistically significant differences in age,pathological G grade,and mean maximal diameter of NENs between the pancreas andother organs( P < 0. 05). In all CT manifestations,the statistically significant differences in enhancing degrees of NENs in arte-rial and venous phases,enhancing uniformity in venous and delayed phases,tumor boundary,shape,and adjacent peritoneal me-tastasis between both were found( P < 0. 05). However,the calcification,pre-contrast density,enhancing uniformity in arterialphase,enhancing degree in delayed phase,enhancing curve type,proximal structure infiltration,vascular invasion,lymph nodemetastasis,distant organ metastasis and ascites were not significantly different( P > 0. 05). Conclusion The biological behav-iors and CT manifestations of NEN in the pancreas and other digestive organs are somewhat different. The enhancing degrees ofNENs in arterial and venous phases,enhancing uniformity in venous and delayed phases,and some others features are helpful forthe identification between both.更多还原