【摘要】 目的探讨新疆维、汉不同民族非瓣膜型房颤的相关影响因素。方法采用病例对照研究的方法,病例选自房颤流行病学调查及2009年8月-2013年5月在新疆医科大学第一附属医院心脏中心等住院的维吾尔族和汉族老年患者,年龄均≥60岁。对照组从相应的流行病学调查和上述收集病例的医院体检、心电图检查无房颤老年者中随机选取。对所有受调查者进行出生年月、吸烟、饮酒、房颤家族史、高血压病史、糖尿病病史、冠心病病史等资料的采集,并行详细体格检查,对相关指标进行检测,对所有收集的房颤相关因素进行多元非条件Logistic回归分析。结果新疆维吾尔族老年人中年龄、肥胖、睡眠呼吸暂停(OSAHS)、高血压,T-ch,Hcy(Hcy)、超敏C反应蛋白(hs-CRP)和白细胞介素-6(IL-6)是维吾尔族非瓣膜型房颤的危险因素;新疆汉族老年人非瓣膜型房颤的危险因素分别是年龄、饮酒、高血压,T-ch,Hcy、hs-CRP和IL-6。结论在维、汉不同民族老年房颤患者中需积极控制高血压和胆固醇水平,诊治过程中需重视Hcy、hs-CRP和IL-6的管理。在维吾尔族人群中,应大力开展房颤的健康教育,调整饮食结构,避免肥胖。在汉族老年人群中需积极宣教戒酒。更多还原

【Abstract】 Objective To explore related factors of AF among Uygur and Han elderly people in Xinjiang. Methods A case-control study was conducted. The cases were collected from epidemiological investigation of atrial fibrillation and aged Uygur and Han elderly patients,aged more than 60 years, who were hospitalized in the heart center of the first affiliated Hospital of Xinjiang Medical University from August 2009 to May 2013. The control group was randomly selected from the elderly patients without atrial fibrillation. The data of birth age, smoking, drinking, family history of atrial fibrillation, history of hypertension, history of diabetes, history of coronary heart disease were collected. Multivariate non-conditional Logistic regression analysis of all collected factors related to atrial fibrillation. Results The risk factors for AF were age,obesity, OSAHS,hypertension, cholesterol, Hcy,hs-CRP and IL-6 among Uygur elderly people; Risk factors for AF among Han elderly people in Xinjiang were age, alcohol, hypertension, cholesterol, Hcy, hs-CRP and IL-6. Conclusion It is necessary to actively control hypertension and cholesterol levels in elderly patients with atrial fibrillation in different nationalities of China and pay attention to the management of Hcy,hs-CRP and IL-6 in the course of diagnosis and treatment. In Uygur population, health education of atrial fibrillation should be carried out vigorously, diet structure should be adjusted to avoid obesity. It is necessary to actively preach and abstinence alcohol among the elderly population of Han nationality.更多还原