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他汀类药物在冠心病合并糖尿病患者治疗中的应用

Application of Statins in the Treatment of Coronary Heart Disease Complicated with Diabetes

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【作者】 崔文章

【Author】 CUI Wen-zhang;Department of Cardiovascular Medicine, Jilin People’s Hospital;

【机构】 吉林省人民医院心内科

【摘要】 目的探讨他汀类药物在冠心病合并糖尿病患者治疗中的应用与效果。方法选取该科2016年11月—2017年11月收治的冠心病合并糖尿病患者128例,随机分为两组各64例,对照组给予常规治疗,观察组在对照组的基础上给予他汀类药物。结果治疗后观察组FPG(5.21±0.78)mmol/L、TC(5.35±0.16)mmol/L、TG(1.18±0.44)mmol/L、LDL-C(2.79±0.19)mmol/L较对照组显著降低,HDL-C(1.88±0.33)mmol/L较对照组显著升高(P<0.05);观察组不良事件发生率为7.8%,明显少于对照组21.9%(P<0.05)。结论对冠心病合并糖尿病患者给予他汀类药物,可有效降低血脂水平,减少心血管不良事件的发生,值得应用。

【Abstract】 Objective This paper tries to investigate the application and effect of statins in the treatment of patients with coronary heart disease and diabetes. Methods 128 patients with coronary heart disease and diabetes mellitus admitted to this hospital from November 2016 to November 2017 were selected and were randomly divided into two groups of 64 patients in each. The control group was given conventional treatment. The observation group was given statins based on the control group. Results After treatment, FPG(5.21±0.78)mmol/L, TC(5.35±0.16)mmol/L, TG(1.18±0.44)mmol/L, and LDL-C(2.79±0.19)mmol/L were significantly lower in the observation group than in the control group. HDL-C(1.88±0.33)mmol/L was significantly higher than that in the control group(P<0.05). The incidence of adverse events in the observation group was7.8%, which was significantly less than 21.9% in the control group(P<0.05). Conclusion Giving statins to patients with coronary heart disease and diabetes can effectively reduce blood lipid levels and reduce the incidence of cardiovascular adverse events. It is worth applying.

【关键词】 他汀类冠心病糖尿病
【Key words】 StatinsCoronary Heart DiseaseDiabetes
  • 【文献出处】 糖尿病新世界 ,Diabetes New World , 编辑部邮箱 ,2018年04期
  • 【分类号】R541.4;R587.1
  • 【被引频次】7
  • 【下载频次】55
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