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深圳市0~5岁儿童流感样病例3种呼吸道病毒的感染情况

Infection situation of three respiratory virus in 0~5-year-old children with influenza-like illness in Shenzhen

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【作者】 杨小柯房师松耿艺介王昕张仁利

【Author】 YANG Xiao-ke;FANG Shi-song;GENG Yi-jie;WANG Xin;ZHANG Ren-li;Shenzhen Center for Disease Control and Prevention;

【机构】 深圳市疾病预防控制中心

【摘要】 目的了解深圳地区0~5岁儿童流感样病例患者中3种呼吸道病毒的感染状况。方法 2016年1-12月,在深圳市2家哨点医院每周采集0~5岁流感样病例患儿的咽拭标本送深圳市疾控中心,对腺病毒(ADV)、呼吸道合胞病毒(RSV)和人偏肺病毒(hMPV)进行荧光定量PCR核酸检测。结果共采集样本2 118份,检出阳性77份,无混合感染病例,其中ADV阳性率为1.13%(24例),hMPV和RSV阳性率分别为1.75%和0.76%(37和16例)。ADV的检出主要集中在12-2月间,RSV 3-5月检出率较高,呈春季流行趋势,hMPV在1月和8月检出率较高。结论 2016年这三种呼吸道病毒在深圳呈较低检出率,但季节性高发需引起临床关注并针对性预防。

【Abstract】 Objective To study the infection situation of three respiratory virus in 0~5-year-old children with influenza-like illness in Shenzhen. Methods From January to December in 2016,throat swab samples of 0~5-year-old children with influenza-like illness were collected weekly in two monitoring hospitals and then sent to Shenzhen Center for Disease Control and Prevention for nucleic acid detection of adenovirus(ADV),respiratory syncytial virus(RSV)and human metapneumovius(hMPV)by fluorescent quantitative PCR. Results 2 118 samples were collected,and 77 samples were positive with no co-infection. The positive rate of ADV was 1.13%(24 samples),and of hMPV and RSV were 1.75% and 0.76%(37 and 16 samples),respectively. The detection rate of ADV was high between December and February. From March to May,RSV was detected to be prevalent. The detection peak was in January and August for hMPV. Conclusion In 2016,the detection rate of these three viruses was relatively low in Shenzhen,but the seasonal epidemic should be noticed and prevented pertinently.

【基金】 广东省医学科学技术研究基金项目(A2016603)
  • 【文献出处】 热带医学杂志 ,Journal of Tropical Medicine , 编辑部邮箱 ,2018年02期
  • 【分类号】R725.1
  • 【被引频次】2
  • 【下载频次】124
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