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血清NGAL及APACHEⅡ评分评估危重症患者急性肾损伤预后

The Value of Serum NGAL and APACHE Ⅱ in Assessing the Prognosis of Acute Kidney Injury for Critical Patients

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【作者】 高金霞李秀元叶虹婷张庆华刘冉李强郭永波

【Author】 GAO JIN-xia;School of Public Health of Mudanjiang Medical College;

【机构】 牡丹江医学院公共卫生学院牡丹江医学院红旗医院牡丹江市第二人民医院牡丹江市第七人民医院

【摘要】 目的分析血清NGAL水平与APACHEⅡ评分在评估患者AKI预后中的价值;方法将入住危重症医学科(ICU)的AKI患者,根据预后将患者分为存活组和死亡组,比较血清NGAL水平与APACHEⅡ分值与患者预后之间的关系;结果两组患者在ICU滞留时间、器官衰竭个数、重症感染、机械通气治疗、休克方面比较,差异有统计学意义(P<0.05);两组患者的Scr、NGAL、APACHEⅡ评分比较,差异有统计学意义(P<0.05),死亡组明显高于存活组;AKI不同分期NGAL、APACHEⅡ分值比较,差异有统计学意义(P<0.05);结论血清NGAL水平及APACHEⅡ评分均与急性肾损伤患者病情严重程度相关,在该类患者预后判断中具有一定的临床指导意义。

【Abstract】 Objective To analyze the level of serum NGAL and the score of APACHE II in evaluating the prognosis of patients with AKI. Methods AKI patients of ICU were separated into survival and death groups,in order to study the relationship between the level of serum NGAL and the score of APACHE II with the prognosis of the patients. Results Compared two groups of patients with detained ICU time,number of organ failure,severe infection,mechanical ventilation treatment and shock,The difference was statistically significant( P < 0. 05); The difference of Scr,NGAL and APACHE II between the two groups were also statistically significant( P < 0. 05). Conclusion The level of blood NGAL and the score of APACHE II were related to the severity of the patients with acute renal injury,there was a certain clinical significance in the prognosis of such patients.

【基金】 黑龙江省教育厅科学技术研究项目(12541848)
  • 【文献出处】 牡丹江医学院学报 ,Journal of Mudanjiang Medical University , 编辑部邮箱 ,2018年02期
  • 【分类号】R692
  • 【下载频次】42
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