【摘要】 目的探讨影响偏头痛患者失能相关因素,为优化偏头痛患者管理提供帮助。方法选择本院门诊178例偏头痛患者,完成偏头痛残疾程度评估量表(MIDAS)和头痛影响测验调查问卷(HIT-6),并记录患者年龄、性别、频率(每月头痛发作次数)、头痛程度评分、初发头痛持续时间、体质量指数(BMI)、广泛性焦虑量表(GAD-7)评分、患者健康问卷抑郁量表(PHQ-9)评分、阿森斯失眠量表(AIS)评分及是否药物滥用、是否先兆性头痛。按MIDAS和HIT-6量表将偏头痛患者分为失能和无失能2组,比较2组年龄、性别、频率(每月头痛发作次数)、头痛程度、初发头痛持续时间、BMI、GAD-7、PHQ-9、是否药物滥用、是否先兆性头痛、是否睡眠障碍。再以与是否失能有统计意义的因素为自变量,是否失能为因变量,进行多元线性回归分析。结果单因素分析显示,是否药物滥用、疼痛程度评分、BMI、频率、PHQ-9评分、GAD-7评分、AIS评分与失能有关(P<0.05)。多因素分析显示,抑郁、焦虑评分、AIS评分未进入回归方程(P>0.05),是否药物滥用、疼痛程度评分、BMI、频率与失能独立相关(P<0.05)。结论偏头痛患者滥用止痛药,发作时头痛程度,发作频率,体质量指数,焦虑影响患者失能。更多还原

【Abstract】 Objective To explore the factors affecting disability of the migraine patients and help to optimize management of the migraine patients. Method 178 patients with clinical diagnosis migraine in our outpatient clinic were recruited, completing migraine disability assessment scal(MIDAS), headache impact test-6(HIT-6) and recording age, sex, frequency(number of headache attacking in a month), degree of headache, duration time of headache attacking, body mass index(BMI), Generalized Anxiety Disorder-7 scale(GAD-7), patient health questionnaire 9-item depression scale(PHQ-9), Athens Insomnia Scale(AIS) and whether substance abuse, Whether aura headache. 178 patients were divided into two groups: disability group and non-disability group by MIDAS and HIT-6 scale, Comparing age, sex, frequency, headache degree, duration of initial headache, score of the BMI, GAD-7, PHQ-9, AIS Scale, whether drug abuse and aura headache between the two groups. Then, taking the factors with statistical significance as independent variables and whether disability as dependent variables, the multivariate Logistic regression analysis was carried out. Results Single factor analysis showed whether drug abuse, pain score, BMI, frequency, PHQ-9, GAD-7, AIS score were related to disability(P<0.05). Multivariate analysis showed that PHQ-9 score,whether insomnia did not enter regression equation(P>0.05), whether drug abuse, pain degree score, GAD-7 score,BMI, frequency and disability independent correlation(P<0.05). Conclusion Migraine patients abuse painkiller, the degree of headache, frequency of attack, weight index and anxiety affect the disability.更多还原