【摘要】 目的:探讨痰液涂片镜检、结核感染T细胞斑点试验(T-SPOT.TB)、血清结核抗体、血沉等四项检测对结核的诊断价值。方法:分别对97例结核患者及27例非结核患者分别进行液涂片镜检、T-SPOT.TB、血清结核抗体、血沉等检测。结果:除血沉外,结核患者液涂片镜检、T-SPOT.TB、血清结核抗体阳性率明显高于非结核患者(P值均<0.05),T-SPOT.TB、血清结核抗体、血沉检出阳性率在涂阴、涂阳结核病患者差异无统计学意义(P值均>0.05)。结论:对结核病检测敏感性:T-SPOT.TB>血沉>血清结核抗体>痰涂片,检测特异性:痰涂片>T-SPOT.TB>血清结核抗体>血沉,T-SPOT.TB检测联合多种实验室方法检测结核,能有效提高结核诊断的准确率。更多还原

【Abstract】 Objective:To explore the diagnostic values of sputum acid-fast bacilli detection, T-SPOT. TB, serum TB antibody and erythrocyte sedimentation rate(ESR) in n patients with tuberculosis(TB).Method:97 patients with tuberculosis and 27 healthy controls were recruited to perform assays of sputum acid-fast bacilli detection, T-SPOT. TB, serum TB antibody and ESR, respectively.Results:The positive rates of sputum acid-fast bacilli detection, T-SPOT. TB and serum TB antibody were significantly higher in TB patients than that in healthy individuals(all P<0.05), while no similar difference was found in ESR levels between two groups. In addition, all above four laboratory indicators were shown no differences between TB patients with positive and negative sputum acid-fast bacilli detection(all P>0.05).Conclusion:Ranking results of sensitivity for TB detection showed that, T-SPOT. TB>ESR>serum TB antibody. Ranking results of detection specificity indicated that, sputum acid-fast bacilli detection>T-SPOT. TB>serum TB antibody>ESR. T-SPOT. TB assay, in combination with the other laboratory indicators, could enhance the Diagnostic accuracy of tuberculosis.更多还原