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The specific cytotoxicities of chimeric antigen receptor-engineered T cells on different lymphomas

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【作者】 张蕊

【Author】 ZHANG Rui;Dept Hematol Oncol,Tianjin 1st Centr Hosp;

【机构】 Dept Hematol Oncol,Tianjin 1st Centr Hosp

【摘要】 <正>Objective To investigate the specific cytotoxicities of the second and the third generations of chimeric antigen receptor(CAR)-engineered T cells(CAR-T)on different lymphomas.Methods CAR-Ts were prepared by lentivirus packaging and infection of T cells.CCK-8,ELISA and Lactate dehydrogenase cytotoxicity assay were applied to detect the proliferation capacity,the secretion

  • 【文献出处】 China Medical Abstracts(Internal Medicine) ,中国医学文摘(内科学分册)(英文版) , 编辑部邮箱 ,2017年04期
  • 【分类号】R733.1
  • 【下载频次】18
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