【摘要】 目的探讨体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)在重症爆发性心肌炎(fulminant myocarditis,FM)中的应用价值。方法回顾性分析2014年2月~2015年7月使用ECMO支持治疗的FM 6例的临床资料。男3例,女3例,年龄(35.7±9.3)岁。均采用股动静脉插管置入静脉-动脉ECMO(veno-arterial ECMO,V-A ECMO)的方式。结果 ECMO辅助(213.0±83.8)h。5例成功脱离ECMO,其中4例生存出院,1例虽脱离ECMO,但死于多脏器功能衰竭;1例死于严重脓毒症。4例出院患者随访6、18、20、5个月,均存活,左心室射血分数(left ventricular ejection fraction,LVEF)分别为65%、66%、55%、71%。结论 ECMO可应用于因重症爆发性心肌炎引起难治心源性休克和致命性心律失常患者。更多还原

【Abstract】 Objective To evaluate effects and functional outcomes of extracorporeal membrane oxygenation( ECMO) for the treatment of fulminant myocarditis. Methods From February 2014 to July 2015,6 patients( 3 male and 3 female; mean age:35. 7 ± 9. 3 years old) with fulminant myocarditis were treated with femoral veno-arterial ECMO for refractory cardiogenic shock and life-threatening arrhythmia. Results The mean duration of ECMO was 213. 0 ± 83. 8 hours. Five patients were successfully weaned from ECMO,include one patient died due to multi-organ failure. The other patient died due to severe sepsis. Four patients were discharged from the hospital,and survival at follow-up for 6,18,20,and 5 months,respectively. The left ventricular ejection fractions( LVEF) were 65%,66%,55%,and 71%,respectively. Conclusion We recommend ECMO in patients with fulminant myocarditis and refractory cardiogenic shock and life-threatening arrhythmia to facilitate myocardial recovery.更多还原