【摘要】 目的应用频域光学相干断层扫描(SD-OCT)观察小切口白内障摘除联合人工晶体植入术后早期黄斑中心区的形态变化,探讨该术式对黄斑区的安全性。方法选取160例(160眼)接受小切口白内障摘除联合人工晶体植入术患者作为病例组,另选取29例健康志愿者作为正常对照组。对两组受检者的双眼采用SD-OCT行黄斑中心凹视网膜厚度及黄斑区容积的检测并进行比较。结果正常对照组右眼黄斑中心凹视网膜厚度为(224.40±14.81)μm,黄斑区容积为(8.62±0.40)mm~3;左眼黄斑中心凹视网膜厚度为(221.05±13.25)μm,黄斑区容积为(8.43±0.46)mm~3,正常对照组右、左眼黄斑中心凹视网膜厚度及黄斑区容积比较差异无统计学意义(P>0.05)。病例组术后3 d及1个月右眼和左眼黄斑中心凹视网膜厚度、黄斑区容积比较差异无统计学意义(P>0.05)。病例组术后3 d及1个月右眼黄斑中心凹视网膜厚度、黄斑区容积与正常对照组比较差异无统计学意义(P>0.05),病例组术后3 d及1个月左眼黄斑中心凹视网膜厚度、黄斑区容积与正常对照组比较差异无统计学意义(P>0.05)。结论小切口白内障摘除联合人工晶体植入术对黄斑中心区的形态影响较小,安全性较高。SD-OCT是观察小切口白内障摘除术后早期黄斑中心区形态变化的有效方法。更多还原

【Abstract】 Objective To observe the morphological changes of macula in early small incision cataract extraction combined with intraocular lens implantation by spectral-domain optical coherence tomography(SDOCT) and discuss the safety of this operation for macular region. Methods There were 160 cases(160 eyes) receiving small incision cataract extraction combined with intraocular lens implantation as case group, and 29 healthy volunteers as normal control group. The macular foveal thickness and macular volume were measured by SD-OCT in the eyes of two groups were compared. Results Normal control group had macular foveal retinal thickness in the right eye as(224.40±14.81) μm, macular volume in the right eye as(8.62±0.40) mm3, and macular foveal retinal thickness in the left eye as(221.05±13.25) μm, macular volume in the left eye as(8.43±0.46) mm~3. There was no statistically significant difference in macular foveal retinal thickness and macular volume between right eyes and left eyes(P>0.05). The case group had no statistically significant difference in macular foveal retinal thickness and macular volume between right eyes and left eyes in postoperative 3 d and 1 month(P>0.05). The case group had no statistically significant difference in macular foveal retinal thickness and macular volume in the right eyes in postoperative 3 d and 1 month, comparing with the normal control group(P>0.05). The case group had no statistically significant difference in macular foveal retinal thickness and macular volume in the left eyes in postoperative 3 d and 1 month, comparing with the normal control group(P>0.05). Conclusion Combination of small incision cataract extraction and intraocular lens implantation has little influence on the shape of morphology of the central region of macula, and has higher safety. SD-OCT is an effective method to observe the morphological changes of central macular in early stage after small incision cataract extraction.更多还原