【摘要】 目的 观察在常规西医治疗基础上联用清胰灌肠方合并针刺治疗对内镜逆行胰胆管造影(ERCP)术后胰腺炎的临床疗效。方法 选取2012年1月至2016年1月于武汉大学人民医院行ERCP术且术后确诊发生胰腺炎的患者150例,根据随机数字表法将患者分为对照组和观察组,备75例。对照组患者接受常规西医治疗,观察组在对照组基础上加用清胰灌肠方并联合针刺治疗。对比2组患者的术后住院时间、症状恢复时间、相关实验室指标恢复正常值时间和临床疗效。结果 观察组患者自主排便恢复时间、腹胀及腹痛消失时间均明显短于对照组[(3.8±1.0)d比(4.8±1.4)d、(5.1±1.5)d比(6.8±2.3)d、(3.1±1.4)d比(4.1±1.6)d],差异均有统计学意义(均P<0.05);2组患者术后住院时间比较,差异无统计学意义(P>0.05)。观察组患者血淀粉酶、白细胞计数、C反应蛋白、碱性磷酸酶恢复正常值时间均明显短于对照组[(4.1±1.2)d比(5.1±1.5)d、(4.3±1.3)d比(5.2±1.7)d、(3.8±1.8)d比(4.9±2.0)d、(6.2±1.8)d比(7.4±2.1)d],差异均有统计学意义(均P<0.05);2组患者尿淀粉酶恢复正常值时间比较,差异无统计学意义(P>0.05)。观察组的整体疗效及痊愈率均明显优于对照组,差异均有统计学意义(均P<0.05)。结论 清胰灌肠方合并针刺治疗ERCP术后急性胰腺炎临床效果明显。更多还原

【Abstract】 Objective To observe the clinical efficacy of western medical therapy in combination with Qingyi Guanchang granules and acupuncture in treating pancreatitis after endoscopic retrograde cholanigiopancreatography(ERCP).Methods Totally 150 patients who had pancreatitis after ERCP from Journal 2012 to Journal2016 in Renmin Hospital of Wuhan University were randomly divided into observation group and control group,with 75 cases in each group.The control group had routine western medical therapy;the observation group was added Qingyi Guanchang granules combined with acupuncture therapy.Postoperative hospitalization time,symptom recovery time,biochemical indexes recovery time and the therapeutic effect were analyzed.Results The first defecation time,abdominal distension disappearing time and abdominal pain disappearing time in observation group were significantly shorter than those in control group[(3.8 ±1.0) d vs(4.8±1.4)d,(5.1±1.5)dvs(6.8±23)d,(3.l±1.4)d vs(4.1 ±1.6)d](P<0.05);postoperative hospitalization time had no significant difference between groups(P > 0.05).Recovery time of hemodiastase,leukocyte count,C-reactive protein and alkaline phosphatase in observation were significantly shorter than those in control group[(4.1 ±1.2)d vs(5.1 ±1.5)d,(4.3±1.3)dvs(5.2±1.7)d,(3.8±1.8)dvs(4.9±2.0)d,(6.2 ± 1.8)dvs(7.4 ±2.l)d](P<0.05);recovery time of urine amylase had no significant difference between groups(P > 0.05).The cure rate and total efficacy in observation group were significantly better than those in control group(P <0.05).Conclusion Qingyi Guanchang granules combined with acupuncture is effective in treating pancreatitis after ERCP.更多还原