【摘要】 目的 探讨妊娠合并风湿性心脏病二尖瓣狭窄患者行经皮球囊二尖瓣成形术(PBMV)的安全性、可行性及术后对妊娠的影响。方法 分析本院自1988年10月至2015年1月33例行PBMV的妊娠合并风湿性心脏病二尖瓣中重度狭窄患者,观察术前、术后血流动力学及妊娠期心功能变化,出院后随访1.5~6.0年胎儿发育情况。结果 手术前后左心房压力、二尖瓣跨瓣压差及二尖瓣瓣口平均面积差异均有统计学意义。33例患者手术均成功,无手术操作相关并发症。术后20例患者自然分娩,13例患者剖腹产,妊娠期及分娩期随访患者无1例发生心衰症状。所有胎儿Apgar评分9~10分。结论 妊娠合并风湿性心脏病二尖瓣中重度狭窄患者对PBMV术有良好的耐受性,手术安全、可行。更多还原

【Abstract】 Objective To investigate the safety and feasibility of percutaneous balloon mitral valvuloplasty(PBMV) on pregnancy women with rheumatic mitral stenosis with mitral stenosis and effect subsequent pregnancy on cardiac function. Methods PBMV was made in 33 pregnancy women(mean age 27.4 years) admitted in our hospital since October 1988 to January 2015, whose clinical and echo cardiographic evaluation were obtained with a follow-up of 1.5-6.0 years. Results The procedure was successful in all 33 pregnancy women, with no severe complication. There was significant difference in left atrial mean pressure, mitral valve pressure gradient and mitral valve area after the procedure. All pregnancy women had normal vaginal deliveries. The children had normal grown and development with the Apgar score of 9-10. No significant change was observed in all echocardiography parameters and no heart failure before pregnancy and after delivery. Conclusion In pregnancy women with symptomatic mitral stenosis, PBMV is feasible, safe and effective.更多还原