【摘要】 目的分析红河州艾滋病病毒感染者和病人中艾滋病相关死亡的影响因素,为有针对性地采取艾滋病防治措施提供参考。方法根据"国家艾滋病综合防治信息系统"中HIV/AIDS病例报告、随访检测、抗病毒治疗随访资料,进一步核实建立数据库,使用Cox比例风险模型分析艾滋病相关死亡的影响因素。结果红河州HIV/AIDS病例中,报病时疾病状态为AIDS(HR=2.106,95%CI:1.906~2.326)、医疗机构就诊发现(HR=1.237,95%CI:1.102~1.388)、未接受过CD4+T淋巴细胞检测(HR=1.553,95%CI:1.390~1.735)、未接受抗病毒治疗(HR=5.007,95%CI:4.471~5.607)、男性(HR=1.568,95%CI:1.403~1.752)、报病时年龄30岁以上、高中及中专及以下文化程度的病例发生艾滋病相关死亡的风险更高。结论继续扩大HIV监测检测工作,及早发现HIV/AIDS病例,接受CD4+T检测和抗病毒治疗可降低HIV/AIDS的死亡风险,延长生存时间。更多还原

【Abstract】 Objective The objective of the study was to analyze the influencing factors of IDS-relateddeaths among HIV/AIDScases in Honghe Prefecture, and thus to provide a reference for targeted AIDS prevention and control. Methods Data of HIV/AIDS case reports, follow-up examinations, anti-viral treatment follow-upsfrom the State Comprehensive AIDS Prevention and Treatment Information System were verified to establish a database for analyzingthe factors influencing AIDSrelated deaths using the Cox proportional hazard model. Results Among the HIV/AIDS cases in Honghe Prefecture, cases having higher risks of AIDS-related deathsare those who were diagnosed with AIDS when reported(HR=2.106,95% CI:1.906-2.326), were diagnosed upon visiting a medical institution(HR =1.237,95% CI:1.102-1.388), had never received a CD4+T lymphocyte detection(HR=1.553,95%CI:1.390-1.735), had never received an anti-viral treatment(HR=5.007,95%CI:4.471-5.607), were male(HR=1.568,95%CI:1.403-1.752), were aged above30 when reported, and had an educational background of high schoolor lower. Conclusion HIV monitoring and detection should be expanded to allow early discovery of HIV/AIDS cases. CD4+T detection and anti-viral treatment may reduce the risk of HIV/AIDS deaths and extend survival time.更多还原