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再现性研究及其在疟疾流行病学研究中的应用

Application of reproducible research theory in malaria epidemiology experiments

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【作者】 王楠谯治蛟李晓松赵星

【Author】 WANG Nan;QIAO Zhi-jiao;LI Xiao-song;ZHAO Xing;Department of Epidemiology and Medical Statistics,West China School of Public Health,Sichuan University;

【机构】 四川大学华西公共卫生学院(华西第四医院)

【摘要】 目的在我国流行病学研究中推广再现性研究这一概念,为其他研究者提供一个新的数据分析过程和结果展示策略。方法以疟疾为例,阐释再现性研究的定义、用法以及意义,并利用其常见实现方式R编程语言中的knitr包进行实例演示。结果公开有关疟疾的建模数据和编程,进行疟疾时间序列分析的再现性研究,从而可建立更加精准的疟疾ARIMA模型。结论再现性研究可为我国流行病学证据的有效性验证提供思路,推进再现性研究在人群疾病和人类健康中的应用。

【Abstract】 Objective To popularize the concept of reproducible research in our field of epidemiologic studies,and to provide a new procedure of data analysis and a fresh strategy of result display to other interested investigators. Methods Malaria data was as the example to explain the definition,direction and significance of the reproducible research,and the knit package of R software environment was used to display the practical experience. Results We opened the data and program of malaria to conduct the reproducible research of time series analysis,so that to establish the more accurate ARIMA model. Conclusion Reproducible research can offer new ideas for validation of epidemiological evidence in our country,and promote the application of this method in the population disease and human health.

【基金】 国家自然科学基金(81502894)
  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2017年01期
  • 【分类号】R531.3;R181.3
  • 【下载频次】144
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