【摘要】 建立了液相色谱质谱法(LC-MS/MS)测定饮用水中4-叔丁基苯酚含量的方法。试样经HLB固相萃取柱富集,叔丁基醚萃取洗脱,丹酰氯衍生化后,采用BEH C18色谱柱分离,三重四级杆质谱仪测定,外标法定量。结果表明:4-叔丁基苯酚在0.5~50.0 ng/m L范围内,具有良好的线性关系,相关系数R2为0.999 8;方法检出限为0.1 ng/m L;加标回收率为85.3%~97.4%,相对标准偏差为0.9%~5.5%。该方法检出限低,准确度高,精密度好。更多还原

【Abstract】 A method for determination of 4-tert-butylphenol in drinking water by liquid chromatography mass spectrometry( LC-MS/MS) is established.The sample is prepared by collecting in HLB solid phase extraction column,then being extracted and eluted by tert butyl ether,and then deriving through dansyl chloride,and finally being separated by BEH C18 chromatography column.The prepared sample is determined by the triple quadrupole mass spectrometer,and quantified by external standard method.The results show that the linear correlation coefficient R~2 is 0. 999 8 in the 4-tertbutylphenol concentration range of 0. 5-50. 0 ng/m L,indicating a good linear relation.The detection limit is 0. 1 ng/m L.The standard recoveries are between 85. 3% and 97. 4%,and the relative standard deviation is between 0. 9% and 5. 5%.This detection method features with low detection limit,high accuracy and good precision.更多还原