【摘要】 目的探索昆明市男男性行为者(MSM)艾滋病病毒(HIV)新发感染率及其影响因素。方法采用同伴推动抽样法招募MSM,建立前瞻性、开放性队列,HIV抗体阴性者进入随访队列,每6个月随访1次,并进行问卷调查和血清学检测。结果共547名MSM纳入队列,HIV新发感染率为5.32/100人年,梅毒新发感染率为5.59/100人年。研究对象的安全套使用情况差异有统计学意义(χ~2=14.852,P<0.05)。非条件Logistic回归分析显示,发生性行为时未坚持使用安全套的MSM,感染HIV的危险性是坚持使用安全套者的3.546倍。结论昆明市MSM的新发感染率达到较高水平,未坚持使用安全套是MSM感染HIV的危险因素。更多还原

【Abstract】 Objective To explore HIV incidence and risk factors among men who have sex with men in Kunming city.Methods Respondent driven sampling(RDS)method was used to recruit MSM in Kunming.An open prospective cohort study was conducted among HIV-seronegative MSM with the follow-ups of every six months.Results A total of 547 MSM was enrolled in the cohort.The incidence rates were 5.32 per 100person-years(PY)for HIV infection and 5.59 per 100PY for syphilis.Condom use(χ~2=14.852)had statistical significance difference(P<0.05).The results of logistic regression showed that the risk of MSM infection in patients who did not adhere to use condoms during sexual activities was 3.546 times higher than that of HIV with those using condoms consistently.Conclusion The HIV incidence rate is high among MSM in Kunming.No consistent use of condoms is a risk factor for HIV infection of MSM.更多还原