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Clinical study of Cangbai Shiduqing Granul in reversing drug resistance of ureaplasma urealyticum

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【作者】 张颖纯李元文李纬周志强赵雅静吴美超石静纹蔡玲玲

【Author】 Zhang Yingchun;Li Yuanwen;Li Wei;Zhou Zhiqiang;Zhao Yajing;Wu Meichao;Shi Jingwen;Cai Lingling;Skin disease Hospital of Dalian;Dongfang Hospital,the Second Affiliated Hospital of Beijing University of Chinese Medicine;

【机构】 Skin disease Hospital of DalianDongfang Hospital,the Second Affiliated Hospital of Beijing University of Chinese Medicine

【摘要】 Ureaplasma Urealyticum(UU) can not only cause a wide range of nongonococcalinfectionsto urogenital tract,but also lead to infertility,sterility,intrauterinefetal infection,abortion or other bad consequences.For males,UU may cause prostatitis,epididymitis and other diseases.With great harm to the human health,UU infection has been taken as one of the most important STDs in China for prevention and cure.However,the drug resistance of UU is increasingly stronger with the widespread use of antibiotics.Many nongonococcal patients with mycoplasma infection often fail to be cured after a long time of treatment,and drug sensitive tests find that,multidrug resistance brings physical and mental pains to patients all the time.Luckily,integrated Chinese traditional and western medicine greatly improves the cure rate,though the mechanism is not clear.There have been many studies on the reversion action and mechanism of TCM on the antibiotic resistance of bacteria,but studies on the reversion to UU drug resistance are deficient.Here we chose some voluntary patients with multidrug resistance as the research objects,who received treatment in my hospital in recent 3 years.They were given the oral administration of self-prescribed Cangbai Shiduqing Granule.Then,Cangbai Shiduqing Granule’s reversion effect on UU drug resistance,namely,the sensitivity transformation situation of drug-resistant antibiotics,was observed.And the observation results are presented in the paper.

【Abstract】 Ureaplasma Urealyticum(UU) can not only cause a wide range of nongonococcalinfectionsto urogenital tract,but also lead to infertility,sterility,intrauterinefetal infection,abortion or other bad consequences.For males,UU may cause prostatitis,epididymitis and other diseases.With great harm to the human health,UU infection has been taken as one of the most important STDs in China for prevention and cure.However,the drug resistance of UU is increasingly stronger with the widespread use of antibiotics.Many nongonococcal patients with mycoplasma infection often fail to be cured after a long time of treatment,and drug sensitive tests find that,multidrug resistance brings physical and mental pains to patients all the time.Luckily,integrated Chinese traditional and western medicine greatly improves the cure rate,though the mechanism is not clear.There have been many studies on the reversion action and mechanism of TCM on the antibiotic resistance of bacteria,but studies on the reversion to UU drug resistance are deficient.Here we chose some voluntary patients with multidrug resistance as the research objects,who received treatment in my hospital in recent 3 years.They were given the oral administration of self-prescribed Cangbai Shiduqing Granule.Then,Cangbai Shiduqing Granule’s reversion effect on UU drug resistance,namely,the sensitivity transformation situation of drug-resistant antibiotics,was observed.And the observation results are presented in the paper.

【基金】 National Natural Science Fund(No:81072811);Beijing Administration of Traditional Chinese Medicine Development Plan in 13th Five-Year of Key Specialty of Dermatology;Project from Human Resources Dept of Dongfang Hospital “Dongfang Famous Doctors”
  • 【文献出处】 World Journal of Integrated Traditional and Western Medicine ,世界中西医结合杂志(英文版) , 编辑部邮箱 ,2017年02期
  • 【分类号】R271;R277.5
  • 【下载频次】24
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