【摘要】 目的:观察旋转手法治疗对腰椎间盘突出症患者静息态脑功能的影响。方法:纳入符合条件的17例腰椎间盘突出症患者,均使用旋转手法治疗。采集患者治疗前后的功能磁共振数据,每次治疗前及治疗后分别记录患者的视觉模拟评分法(VAS)评分。结果:治疗后,患者双侧枕上回、左侧枕中回、双侧楔叶、左侧踞状回的低频振荡振幅(ALFF)较治疗前增高,差异有统计学意义(P<0.05)。每次治疗前的VAS评分与每次治疗后的VAS评分均持续下降,差异均有统计学意义(P<0.01)。4次治疗后的VAS评分均低于同期治疗前,差异有统计学意义(P<0.01)。第2次治疗前与第1次治疗后、第3次治疗前与第2次治疗后以及第4次治疗前与第3次治疗后的VAS评分比较,差异均有统计学意义(P<0.05)。结论:旋转手法治疗腰椎间盘突出症,镇痛效果明显,可能通过激活部分脑区实现。更多还原

【Abstract】 Objective:To observe the effect of rotatory manipulation on brain function in resting state in patients with lumbar disc herniation. Methods : Seventeen cases of patients with lumbar disc herniation according to standards were all treated with four times of rotatory manipulation. Collected the functional magnetic resonance data of patients before and after treatment,and recorded visual analogue scale(VAS) score before and after treatment. Results :After treatment,amplitude of low frequency fluctuation(ALFF) of bilateralupper occipital gyrus,left middle occipital gyrus,bilateral cuneus and left calcarine gyrus were all increased when compared with those before treatment(P<0.05). Before each of the four times of treatment and after treatment,VAS scores were declined continually(P<0.01). After each of four times of treatment,VAS scores were all lower than those before this treatment time(P<0.01). The differences of VAS scores before the 2nd treatment and after 1st treatment, before the 3rd treatment and after 2nd treatment, and before the 4th treatment and after 3rd treatment were significant(P<0.05). Conclusion:Rotatory manipulation for lumbar disc herniation has obvious analgesia effect which may be realized by activating some brain regions.更多还原